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HPSE Produkte

(Heparanase (HPSE))
Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

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Ausgewählte HPSE Kategorien

HPSE Antikörper

High quality antibodies with extensive validation data.

HPSE ELISA Kits

Reliable ELISA kits for a wide range of species.

HPSE Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene HPSE Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7438439
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Rat
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7437449
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7438010
Menge 100 μL
Datenblatt Datenblatt

Empfohlene HPSE ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN6574194
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (3)
  • (5)
Kat. Nr. ABIN6730979
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967351
Menge 96 tests
Datenblatt Datenblatt

Empfohlene HPSE Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Synthetic
Validierungen
  • (3)
Kat. Nr. ABIN1880256
Menge 200 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1307050
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7490767
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HPSE Produkten

Jäkel, Bergmann, Toth, Assenov, van der Duin, Strobel, Hank, Klöppel, Dorrell, Grompe, Moss, Dor, Schirmacher, Plass, Popanda, Schmezer: "Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability." in: Nature communications, Vol. 8, Issue 1, pp. 1323, (2018) (PubMed).

Zhao, Liu, Ten, Zhang, Yuan, Yu, An: "Plasma heparanase is associated with blood glucose levels but not urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage." in: Renal failure, Vol. 39, Issue 1, pp. 698-701, (2018) (PubMed).

Qin, Xu, Qi, Guo, Wang, Xu, Qiao, Gu, Niu: "Evaluation of the C-domain of heparanase during AGE-induced macrophage inflammatory response." in: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 1017-1022, (2017) (PubMed).

Liao, Wang, Hu, Liu, Shen, Zhang, Yu, Fan, Zhou: "PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resection." in: Tumour biology, Vol. 37, Issue 3, pp. 2987-98, (2016) (PubMed).

Masola, Zaza, Gambaro, Onisto, Bellin, Vischini, Khamaysi, Hassan, Hamoud, Nativ, N Heyman, Lupo, Vlodavsky, Abassi: "Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury." in: PLoS ONE, Vol. 11, Issue 7, pp. e0160074, (2016) (PubMed).

Zeng, Yao, Chen, Yan, Liu, Zhang, Feng, Wu, Liu: "Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop." in: Oncotarget, Vol. 7, Issue 39, pp. 63324-63337, (2016) (PubMed).

Hu, Atik, Yu, Li, Zhang, Li, Cai, Yu, Chen, Li, Yuan: "Serum heparanase concentration and heparanase activity in patients with retinal vein occlusion." in: Acta ophthalmologica, Vol. 95, Issue 1, pp. e62-e66, (2016) (PubMed).

Qing, Zhang, Chen, Li, Mao, Chen: "High glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpression." in: Journal of cellular and molecular medicine, Vol. 19, Issue 6, pp. 1366-74, (2015) (PubMed).

Hu, Zhang, Jin, Zhu, Xu, Wu, Wang, Chen, Webster, Chen, Yu, Wang: "Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 6, pp. 1850-62, (2015) (PubMed).

Chen, Zhang, Sun, Hu, Lu, Ma: "Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanase." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 4903-12, (2015) (PubMed).

Synonyme und alternative Namen zu HPSE

heparanase (HPSE), heparanase (hpse), heparanase (Hpse), Hep, hpa, HPA, Hpa, hpa1, HPA1, hpr1, HPR1, Hpr1, HPSE, hpse1, HPSE1, hse1, HSE1, im:7144134

Bezeichner auf Proteinebene für HPSE

  • heparanase
  • endo-glucoronidase
  • heparanase-1
  • endoglycosidase heparanase
  • heparanase-like
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