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HRK Produkte

(Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))

Kategorien

This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

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Ausgewählte HRK Kategorien

HRK Antikörper

High quality antibodies with extensive validation data.

HRK ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene HRK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN543406
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN2474088
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN388104
Menge 400 μL
Datenblatt Datenblatt

Empfohlene HRK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1120325
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1120326
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1120327
Menge 96 tests
Datenblatt Datenblatt

Empfohlene HRK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3120786
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3109329
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HRK Produkten

Lucas, Milani, Butterworth, Carmell, Scott, Clark, Cohen, Varadarajan: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." in: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).

Conery, Centore, Spillane, Follmer, Bommi-Reddy, Hatton, Bryant, Greninger, Amzallag, Benes, Mertz, Sims: "Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response." in: Cancer research, Vol. 76, Issue 6, pp. 1313-9, (2016) (PubMed).

Nakamura, Ishida, Shimada, Nakase, Sakaki, Konishi: "Frequent HRK inactivation associated with low apoptotic index in secondary glioblastomas." in: Acta neuropathologica, Vol. 110, Issue 4, pp. 402-10, (2005) (PubMed).

Sunayama, Ando, Itoh, Tomiyama, Sakurada, Sugiyama, Kang, Tashiro, Gotoh, Kuchino, Kitanaka: "Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32." in: Cell death and differentiation, Vol. 11, Issue 7, pp. 771-81, (2004) (PubMed).

Wakabayashi, Kosaka, Hommura: "Up-regulation of Hrk, a regulator of cell death, in retinal ganglion cells of axotomized rat retina." in: Neuroscience letters, Vol. 318, Issue 2, pp. 77-80, (2002) (PubMed).

Sanz, Mellstrom, Link, Naranjo, Fernandez-Luna: "Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells." in: The EMBO journal, Vol. 20, Issue 9, pp. 2286-92, (2001) (PubMed).

Lockshin, Osborne, Zakeri: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, (2000) (PubMed).

Synonyme und alternative Namen zu HRK

harakiri, BCL2 interacting protein (HRK), harakiri, BCL2 interacting protein (contains only BH3 domain) (Hrk), harakiri, BCL2 interacting protein (Hrk), AI838259, Bid3, DP5, Dp5, HARAKIRI, harakiri

Bezeichner auf Proteinebene für HRK

  • BCL2-interacting protein
  • BH3-interacting domain-containing protein 3
  • activator of apoptosis Hrk
  • activator of apoptosis harakiri
  • death protein 5
  • neuronal death protein DP5
  • BH3 interacting (with BCL2 family) domain, apoptosis agonist
  • BH3 interacting domain 3
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