anti-Lumican (LUM) Antikörper

Bezeichnung:: anti-Lumican Antikörper (LUM)

Auf www.antikoerper-online.de finden Sie aktuell 83 Lumican (LUM) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Lumican Kits (40) und Lumican Proteine (19) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 151 Lumican Produkte verfügbar.

Synonyme:: DKFZp468L1116, Ldc, MGC64527, SLRR2D, zgc:86661

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	LUM	4060	P51884
	LUM	17022	P51885
	LUM	81682	P51886
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-Lumican (LUM) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Human Antikörper:

anti-Mouse (Murine) Antikörper:

anti-Rat (Rattus) Antikörper:

Alle verfügbaren anti-Lumican Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Verknüpfte Pathways mit anti-Lumican Antikörper

Glycosaminoglycan Metabolic Process

Weitere Produktkategorien zu Lumican Antikörper

Am meisten referenzierte anti-Lumican Antikörper

Human Polyclonal LUM Primary Antibody für IHC, IHC (p) - ABIN4331833 : Pan, Chen, Stevens, Bronner, May, Tamura, McIntosh, Brentnall: Proteomics portrait of archival lesions of chronic pancreatitis. in PLoS ONE 2011 (PubMed)
Show all 4 Pubmed References
Human Polyclonal LUM Primary Antibody für WB - ABIN517580 : Gasimli, Stansfield, Nairn, Liu, Paluh, Yang, Dordick, Moremen, Linhardt: Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells. in Glycoconjugate journal 2013 (PubMed)
Show all 2 Pubmed References
Human Polyclonal LUM Primary Antibody für WB - ABIN4893953 : Zhao, Li, Xu, He, Cui, Lv: Lumican alleviates hypertrophic scarring by suppressing integrin-FAK signaling. in Biochemical and biophysical research communications 2016 (PubMed)

Weitere Antikörper gegen Lumican Interaktionspartner

Horse (Equine) Lumican (LUM) Interaktionspartner

temporal expression of LUM mRNA during dermal wound repair in the horse

Zebrafish Lumican (LUM) Interaktionspartner

the role of lumican in the development of axial myopia

Human Lumican (LUM) Interaktionspartner

Cancer-associated fibroblast-derived Lumican contributes to tumorigenesis and metastasis of gastric cancer
Lumican and versican (zeige Vcan Antikörper) protein expression are associated with colorectal adenoma-to-carcinoma progression
Lumican is downregulated in the process of scar formation and alleviates hypertrophic scarring by suppressing integrin-FAK (zeige PTK2 Antikörper) signaling.
ectopic mutant lumican (L199P) may induce enlargement of axial lengths and abnormal structures and distributions of collagen fibrils in mouse sclera
Quantitative polymerase chain reaction for messenger RNA expression from tissue specimens revealed significantly higher expression of Biglycan (zeige BGN Antikörper) (p = 0.0008) and Lumican (p = 0.01) and lower expression of Decorin (zeige DCN Antikörper) (p < 0.0001) in urothelial carcinoma of bladder
analysis of decorin (zeige DCN Antikörper) and lumican expression in fibroblasts correlated with palmoplantar collagen bundle size
fibroblasts stimulated with the fibrocyte-secreted inflammatory signal tumor necrosis factor-alpha (zeige TNF Antikörper) secrete the small leucine-rich proteoglycan (zeige Vcan Antikörper) lumican.
This meta-analysis suggests that LUM polymorphisms are associated with the risk of high myopia.
The results suggest that regions within LUM is associated with ACL (zeige ACLY Antikörper) injury susceptibility and that genetic sequence variability within genes encoding proteoglycans may potentially modulate the ligament fibril properties.
meta-analysis, including 1,545 subjects from 5 studies, indicated that Chinese lumican rs3759223 C allele carriers had a decreased risk of high myopia in comparison to T allele carriers

Mouse (Murine) Lumican (LUM) Interaktionspartner

this study shows that Lum negatively regulates encephalitic TH17 cells, implicating a potential therapeutic pathway in TH17 cell mediated autoimmune and inflammatory diseases
ectopic mutant lumican (L199P) may induce enlargement of axial lengths and abnormal structures and distributions of collagen fibrils in mouse sclera
alternations of lumican might be implicated in the pathogenesis of cardiac fibrosis
LUM may coordinate multiple factors of collagen assembly in the murine heart.
Lumican and biglycan (zeige BGN Antikörper) influence corneal keratocyte lamellipodia organization and are critical in the regulation of stromal collagen fibrillogenesis.
Alterations in glycosylated lumican core protein might be implicated in myocardial remodeling and reverse remodeling, with a potential important role for CS/DS GAG chain-synthesizing enzymes.
pro-inflammatory cytokine TNF-alpha (zeige TNF Antikörper) was comparably low 24 hours after infection, but significantly higher in the Lum(-/-) compared to Lum(+/-) infected corneas by 2-5 days after infection
lumican present in the reactive stroma surrounding prostate primary tumors plays a restrictive role on cancer progression
To investigate the functional role of lumican in hepatic fibrosis, lumican null (Null) and wild-type (WT) littermates were administered carbon tetrachloride intra-peritoneally. Hepatic fibrosis was greatly reduced in null animals.
lumican has a major protective role in gram-negative bacterial infections, a novel function for small leucine-rich repeat proteoglycans.

Cow (Bovine) Lumican (LUM) Interaktionspartner

These results suggest that lumican plays a pivotal role in the development of tissue engineered cartilage and that regulation of this protein may be important for the production of high-quality implants.

Rabbit Lumican (LUM) Interaktionspartner

Lumican is downregulated in the process of scar formation and alleviates hypertrophic scarring by suppressing integrin-FAK (zeige PTK2 Antikörper) signaling.
FGF-2 (zeige FGF2 Antikörper)- and TGF-beta1 (zeige TGFB1 Antikörper)-activation of JNK (zeige MAPK8 Antikörper) signaling pathway may be partly responsible for the downregulation of keratocan (zeige KERA Antikörper) and lumican expression in activated corneal keratocytes observed during corneal stromal wound healing.

Lumican (LUM) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

Alternative names and synonyms associated with Lumican (LUM)

lumican (LUM) Antikörper
lumican L homeolog (lum.L) Antikörper
lumican (lum) Antikörper
lumican (CpipJ_CPIJ010209) Antikörper
lumican (Lum) Antikörper

DKFZp468L1116 Antikörper
Ldc Antikörper
MGC64527 Antikörper
SLRR2D Antikörper
zgc:86661 Antikörper

Bezeichner auf Proteinebene für anti-Lumican (LUM) Antikörper

lumican , zlum , Keratan sulfate proteoglycan lumican , KSPG lumican , keratan sulfate proteoglycan lumican , lumican proteoglycan , KSPG , corneal keratan sulfate proteoglycan 37B core protein , keratan sulfate proteoglycan

GENE ID	SPEZIES
100009681	Equus caballus
379493	Xenopus laevis
415149	Danio rerio
452119	Pan troglodytes
482599	Canis lupus familiaris
496415	Xenopus (Silurana) tropicalis
709830	Macaca mulatta
6043170	Culex quinquefasciatus
100126729	Papio anubis
100171487	Pongo abelii
100195033	Salmo salar
100595797	Nomascus leucogenys
4060	Homo sapiens
17022	Mus musculus
81682	Rattus norvegicus
100152607	Sus scrofa
280847	Bos taurus
417891	Gallus gallus
100008665	Oryctolagus cuniculus
100732503	Cavia porcellus

Ausgewählte Anbieter für anti-Lumican (LUM) Antikörper

Haben Sie etwas anderes gesucht?

Telefon:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antikoerper-online.de

Show all anti-Lumican (LUM) Antikörper with Pubmed References