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GCAP1 Proteine

(Guanylate Cyclase Activator 1A (Retina) (GUCA1A))
This gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, the phototransduction messeneger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by decreasing Ca(2+) concentrations following photobleaching. The protein encoded by this gene, guanylyl cyclase activating protein 1 (GCAP1), mediates the sensitivity of GC1 to Ca(2+) concentrations. GCAP1 promotes activity of GC1 at low Ca(2+) concentrations and inhibits GC1 activity at high Ca(2+) concentrations. Mutations in this gene cause autosomal dominant cone dystrophy (COD3)\; a disease characterized by reduced visual acuity associated with progressive loss of color vision. Mutations in this gene prohibit the inactivation of RetGC1 at high Ca(2+) concentrations\; causing the constitutive activation of RetGC1 and, presumably, increased cell death. This gene is expressed in retina and spermatagonia. [provided by RefSeq, Feb 2009].

5 Treffer :

GUCA1A Spezies: Human Wirt: Wheat germ Recombinant ELISA, AP, AA, WB
Produktnummer ABIN1306200
 
GUCA1A Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2721755
 
GUCA1A Spezies: Rind (Kuh) Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7584603
 
GUCA1A Spezies: Huhn Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN1458716
 
GUCA1A Spezies: Rana pipiens Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN1656072
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
    • Western Blotting (WB)
  • Reaktivität
    • Human
    • Chicken
    • Cow
    • Rana pipiens
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Yeast
    • HEK-293 Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 2-205
    • AA 1-201
    • AA 2-199
  • Konjugat
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
  • Hersteller
    • CUSABIO
    • OriGene
    • antibodies-online

Aliase für GCAP1 Proteine

guanylate cyclase activator 1A (GUCA1A) Proteine
guanylate cyclase activator 1A (Guca1a) Proteine
guanylate cyclase activator 1A L homeolog (guca1a.L) Proteine
guanylate cyclase activator 1A (retina) (guca1a) Proteine
guanylate cyclase activator 1a (retina) (Guca1a) Proteine
guanylate cyclase activator 1A (guca1a) Proteine
C6orf131 Proteine
COD3 Proteine
CORD14 Proteine
dJ139D8.6 Proteine
GC-A Proteine
GCAP Proteine
GCAP1 Proteine
Gcap1 Proteine
gcap1 Proteine
GUCA Proteine
GUCA1 Proteine
Guca1 Proteine
GUCA1A Proteine
guca1a Proteine
MGC84170 Proteine
MGC146317 Proteine
mGCAP1 Proteine
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