G6PC Produkte
(Glucose 6-Phosphatase, Catalytic (G6PC))
Kategorien
Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011].
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Ausgewählte G6PC Kategorien
G6PC Antikörper
High quality antibodies with extensive validation data.
G6PC ELISA Kits
Reliable ELISA kits for a wide range of species.
G6PC Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene G6PC Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN2781770
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN651417
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation
WB
Validierungen
- (3)
- (3)
Kat. Nr.
ABIN2781769
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene G6PC ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956119
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956120
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956121
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene G6PC Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354607
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3097500
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3133872
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren G6PC Produkten
: "Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway." in: Molecular and cellular biochemistry, (2023) (PubMed).: "Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction." in: Cell metabolism, Vol. 30, Issue 6, pp. 1141-1151.e5, (2019) (PubMed).
: "Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates." in: Nature medicine, Vol. 23, Issue 4, pp. 439-449, (2017) (PubMed).
: "Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling." in: Nature communications, Vol. 7, pp. 10592, (2016) (PubMed).
: "Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice." in: Nature medicine, Vol. 20, Issue 11, pp. 1263-9, (2014) (PubMed).
: "Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 8, pp. 3339-50, (2014) (PubMed).
: "Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2689-700, (2013) (PubMed).
: "Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis." in: PLoS ONE, Vol. 8, Issue 7, pp. e70309, (2013) (PubMed).
Synonyme und alternative Namen zu G6PC
glucose-6-phosphatase, catalytic (G6pc), glucose-6-phosphatase catalytic subunit (G6PC), glucose-6-phosphatase, catalytic subunit (G6pc), AW107337, G-6-Pase, G6Pase, G6PC1, G6pt, G6PT, Glc-6-Pase, GSD1, GSD1aBezeichner auf Proteinebene für G6PC
- G-6-Pase
- Glc-6-Pase-alpha
- glucose-6-phosphatase
- G6Pase
- G6Pase-alpha
- glucose-6-phosphatase alpha
- glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease)
- glucose-6-phosphatase catalytic subunit
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- G Protein-Coupled Receptor 132
- G Protein-Coupled Receptor 128
- G Protein-Coupled Receptor 126
- G Protein-Coupled Receptor 12
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