FUS Proteine
(Fused in Sarcoma (FUS))
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].
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FUS
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
ELISA, WB
1 image
FUS
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
5 Referenzen
FUS
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, ELISA, WB
FUS
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, ELISA, WB
FUS
Spezies: Human respiratory syncytial virus A
Wirt: Hefe
Recombinant
> 90 %
SDS
1 image
FUS
Spezies: Human respiratory syncytial virus B
Wirt: Hefe
Recombinant
> 90 %
SDS
1 image
FUS
Spezies: Canine Distemper Virus (CDV)
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
FUS
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
95 %
ELISA
1 image
Aktuelle Publikationen für unsere FUS Proteine
: "Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity." in: Cell reports, Vol. 24, Issue 3, pp. 529-537.e4, (2018) (PubMed).: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." in: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).
: "Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways." in: Acta neuropathologica, Vol. 132, Issue 2, pp. 175-96, (2016) (PubMed).
: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).
: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).
Aliase für FUS Proteine
FUS RNA binding protein (FUS) Proteinefused in sarcoma (Fus) Proteine
FUS RNA binding protein (Fus) Proteine
fused in sarcoma (FUS) Proteine
ALS6 Proteine
D430004D17Rik Proteine
D930039C12Rik Proteine
ETM4 Proteine
FUS/TLS Proteine
FUS1 Proteine
Fus1 Proteine
HNRNPP2 Proteine
POMP75 Proteine
TLS Proteine
Tls Proteine
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