FCGR3A Proteine
(Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | Produkt | Reaktivität | Wirt / Klonalität | Anwendung | Preis & Lieferzeit |
|---|---|---|---|---|---|
| FCGR3A Protein (AA 24-190) (His tag) | Maus | Bacteria |
|
361,90 €
Preis anzeigen
|
|
| FCGR3A Protein (AA 1-208) (His tag) | Human | Eukaryota |
|
361,90 €
Preis anzeigen
|
|
| FCGR3A Protein (AA 26-108) (His tag) | Human | Bacteria |
|
302,50 €
Preis anzeigen
|
|
| FCGR3A Protein (AA 17-208) (His tag) | Human | Bacteria |
|
361,90 €
Preis anzeigen
|
|
| FCGR3A Protein (Fc Tag) | Cynomolgus | HEK-293 Cells |
|
584,62 €
Preis anzeigen
|
|
| FCGR3A Protein (His tag) | Human | Escherichia coli (E. coli) |
|
503,00 €
Preis anzeigen
|
|
| FCGR3A Protein (His tag) | Human | Escherichia coli (E. coli) |
|
503,00 €
Preis anzeigen
|
|
| FCGR3A Protein (AA 17-208, V176F) (His tag) | Human | Human Cells |
|
792,31 €
Preis anzeigen
|
|
| FCGR3A Protein (His tag) | Human | Mammalian Cells |
|
730,00 €
Preis anzeigen
|
|
| FCGR3A Protein (His tag) | Human | Human Cells |
|
537,90 €
Preis anzeigen
|
|
| FCGR3A Protein (His tag) | Human | Human Cells |
|
581,90 €
Preis anzeigen
|
Produktnummer ABIN7819796
361,90 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 4 bis 5 Werktagen
Produktnummer ABIN7813472
361,90 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 4 bis 5 Werktagen
Produktnummer ABIN7815266
302,50 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 4 bis 5 Werktagen
Produktnummer ABIN7815267
361,90 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 4 bis 5 Werktagen
Protein
- Spezies
- Cynomolgus
- Wirt
- HEK-293 Cells
- Protein-Typ
- Recombinant
- Reinheit
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7794637
584,62 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
Lieferung nach:
Deutschland
Lieferung in 6 bis 9 Werktagen
Protein
- SDS (SDS-PAGE: Angegebene Anwendung)
- WB (Western Blotting: Angegebene Anwendung)
- Imm (Immunogen: Angegebene Anwendung)
- ELISA (ELISA: Angegebene Anwendung)
- Spezies
- Human
- Wirt
- Escherichia coli (E. coli)
- Protein-Typ
- Recombinant
Produktnummer ABIN7941317
503,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 12 bis 17 Werktagen
Protein
- SDS (SDS-PAGE: Angegebene Anwendung)
- WB (Western Blotting: Angegebene Anwendung)
- Imm (Immunogen: Angegebene Anwendung)
- ELISA (ELISA: Angegebene Anwendung)
- Spezies
- Human
- Wirt
- Escherichia coli (E. coli)
- Protein-Typ
- Recombinant
Produktnummer ABIN7950993
503,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 12 bis 17 Werktagen
Protein
- SDS (SDS-PAGE: Angegebene Anwendung)
- WB (Western Blotting: Angegebene Anwendung)
- ELISA (ELISA: Angegebene Anwendung)
- MS (Mass Spectrometry: Angegebene Anwendung)
- Spezies
- Human
- Wirt
- Human Cells
- Protein-Typ
- Recombinant
- Reinheit
- Greater than 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7314144
792,31 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 5 bis 6 Werktagen
Protein
- SDS (SDS-PAGE: Angegebene Anwendung)
- WB (Western Blotting: Angegebene Anwendung)
- Imm (Immunogen: Angegebene Anwendung)
- ELISA (ELISA: Angegebene Anwendung)
- Spezies
- Human
- Wirt
- Mammalian Cells
- Protein-Typ
- Recombinant
Produktnummer ABIN7946819
730,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 12 bis 17 Werktagen
Protein
- Spezies
- Human
- Wirt
- Human Cells
- Protein-Typ
- Recombinant
- Reinheit
- Greater than 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7959459
537,90 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 12 bis 17 Werktagen
Protein
- Spezies
- Human
- Wirt
- Human Cells
- Protein-Typ
- Recombinant
- Reinheit
- Greater than 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7961605
581,90 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 12 bis 17 Werktagen
Aktuelle Publikationen für unsere FCGR3A Proteine
: "FcγR Binding and ADCC Activity of Human IgG Allotypes." in: Frontiers in immunology, Vol. 11, pp. 740, (2020) (PubMed).
: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." in: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).
: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).
: "Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies." in: Cancer biology & therapy, pp. 1-9, (2019) (PubMed).
: "Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody." in: mAbs, Vol. 10, Issue 6, pp. 864-875, (2019) (PubMed).
: "Charge variant analysis of proposed biosimilar to Trastuzumab." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 46, pp. 46-56, (2017) (PubMed).
: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).
: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).
: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." in: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).
: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).
: "Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies." in: Cancer biology & therapy, pp. 1-9, (2019) (PubMed).
: "Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody." in: mAbs, Vol. 10, Issue 6, pp. 864-875, (2019) (PubMed).
: "Charge variant analysis of proposed biosimilar to Trastuzumab." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 46, pp. 46-56, (2017) (PubMed).
: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).
: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).
Aliase für FCGR3A Proteine
Fc fragment of IgG receptor IIIa (FCGR3A) ProteineFc fragment of IgG receptor IIIa (Fcgr3a) Proteine
CD16 Proteine
CD16A Proteine
FCG3 Proteine
FCGR3 Proteine
Fcgr4 Proteine
FCGRIII Proteine
FCR-10 Proteine
FCRIII Proteine
FCRIIIA Proteine
IGFR3 Proteine
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