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anti-Human CTH Antikörper:
anti-Mouse (Murine) CTH Antikörper:
anti-Rat (Rattus) CTH Antikörper:
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Human Monoclonal CTH Primary Antibody für ELISA, WB - ABIN560521
Schicho, Krueger, Zeller, Von Weyhern, Frieling, Kimura, Ishii, De Giorgio, Campi, Schemann: Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon. in Gastroenterology 2006
Show all 21 Pubmed References
Human Monoclonal CTH Primary Antibody für IHC (p), ELISA - ABIN560523
Siebert, Cantré, Eipel, Vollmar: H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of K(ATP) channels. in American journal of physiology. Gastrointestinal and liver physiology 2008
Show all 7 Pubmed References
Human Monoclonal CTH Primary Antibody für ELISA, WB - ABIN560522
dEmmanuele di Villa Bianca, Sorrentino, Maffia, Mirone, Imbimbo, Fusco, De Palma, Ignarro, Cirino: Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation. in Proceedings of the National Academy of Sciences of the United States of America 2009
Show all 5 Pubmed References
Cow (Bovine) Polyclonal CTH Primary Antibody für WB - ABIN2782463
Moore, Malats, Rothman, Real, Kogevinas, Karami, García-Closas, Silverman, Chanock, Welch, Tardón, Serra, Carrato, Dosemeci, García-Closas: Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer. in International journal of cancer. Journal international du cancer 2007
Show all 4 Pubmed References
Human Polyclonal CTH Primary Antibody für IF (p), IHC (p) - ABIN1387469
Shiina, Shima, Horii, Naitou, Nakamori, Sano, Shimizu: Inhibitory action of hydrogen sulfide on esophageal striated muscle motility in rats. in European journal of pharmacology 2016
Cow (Bovine) Polyclonal CTH Primary Antibody für IHC, WB - ABIN2782464
Yang, Cao, Wu, Wang: Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1. in The Journal of biological chemistry 2004
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Study demonstrated that lower abundance of cystathionine gamma-lyase expression and H2S production enhances type-2 immunoreaction and renders a higher incidence of allergic asthma at a young age.
MicroRNA-186 promotes macrophage lipid accumulation and pro-inflammatory cytokine secretion by targeting cystathionine gamma-lyase in THP-1 (zeige GLI2 Antikörper) macrophages
Inducible expression of CBS (zeige CBS Antikörper) and CSE (zeige CSE Antikörper) was found to be associated with a mineralizing phenotype in mesenchymal stem cells transitioning to mineralizing osteoblasts.
ur findings suggest that these two families of amines inhibit cystathionine-gamma-lyase (CSE) to varying extents, which directly results in altered levels of intracellular HCY and consequent changes in Human vascular smooth muscle cells proliferation.
Lipopolysaccharide increases the expression of CSE (zeige CSE Antikörper) in human macrophages, increasing H2S synthesis, via ERK (zeige EPHB2 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) pathway.
Nox4 (zeige NOX4 Antikörper) is a positive transcriptional regulator of cystathionine-gamma-lyase in endothelial cells.
The expression of CSE (zeige CSE Antikörper) was positively correlated with the severity of gastric ulcer
Our study demonstrates that CSE (zeige CSE Antikörper)/H2S system is regulated by miR (zeige MLXIP Antikörper)-216a, and regulates ABCA1 (zeige ABCA1 Antikörper)-mediated cholesterol efflux and cholesterol levels through the PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) pathway.
Collectively, our findings indicate that radiation could promote HCC (zeige FAM126A Antikörper) cell invasion through EMT (zeige ITK Antikörper) mediated by endogenous H2S/CSE (zeige CSE Antikörper) signaling via the p38MAPK (zeige MAPK14 Antikörper) pathway.
3-Mercaptopyruvate sulphurtransferase and not cystathionine gamma-lyase is the primary regulator of coronary artery hydrogen sulfide (zeige SQRDL Antikörper) production and function.
Exogenous administration of CO exacerbated allergic symptoms, resulting in higher levels of both CO and heme oxygenase-1 (zeige HMOX1 Antikörper) expression, and a further reduction in H2S levels and CSE (zeige CSE Antikörper) expression.
Data show that CSE plays an important role as an inhibitor of inflammation in the liver by producing H2S from L-cysteine.
Study shows maintaining CSE expression is critically important for stress adaptation during posttraumatic acute lung injury and CS-induced COPD (zeige ARCN1 Antikörper), most likely in a gender-dependent manner.
CSE-derived H2S contributes to mouse uterus homeostasis. Sildenafil reduces uterus contractility and its effect involves CSE-derived H2S.
The antiatherosclerotic effect of estrogen is mediated by CSE-generated H2S
Cystathionine-Gamma-Lyase Gene Deletion is associated with reduced inflammation and liver damage.
this study reveals the molecular basis for the differential expression of Cth in mouse models of essential hypertension under basal and pathophysiological conditions.
the findings of this study indicate that a deficiency in 3MST does not significantly affect endotoxemia, while a deficiency in CBS (zeige CBS Antikörper) or CSE slightly ameliorates the outcome of LPS (zeige TLR4 Antikörper)-induced endotoxemia in vivo.
lung MPO (zeige MPO Antikörper) activity increased following induction of sepsis with CLP (zeige HAPLN1 Antikörper) while siRNA treatment significantly reduced MPO (zeige MPO Antikörper) activity. Liver and lung cytokine and chemokine (zeige CCL1 Antikörper) levels in CLP (zeige HAPLN1 Antikörper)-induced sepsis reduced following treatment with siRNA. These findings show a crucial pro-inflammatory role for H2S synthesized by CSE in macrophages in sepsis and suggest CSE gene silencing with siRNA as a potential therapeutic approach for this co
H2S augmented the S-sulfhydration of the rate-limiting gluconeogenic enzymes and PGC-1alpha and increased their activities, which were lower in untreated : To investigate the regulation of hepatic glucose production by cystathionine gamma-lyase KO hepatocytes
Endogenous cystathionine gamma-lyase/Hydrogen sulfide (zeige SQRDL Antikörper) regulates ischaemic vascular remodelling mediated during hind limb ischaemia through NO-dependent monocyte recruitment
This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
, cystathionase (cystathionine gamma-lyase)
, cysteine desulfhydrase
, cysteine-protein sulfhydrase
, homoserine deaminase
, homoserine dehydratase
, CTL target antigen
, probasin-related antigen