CTH Antikörper (N-Term)

Produktnummer ABIN6261082

Produktdetails anti-CTH Antikörper

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: CTH Antibody detects endogenous levels of total CTH.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CTH, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Andere Bezeichnung: CTH (CTH Produkte)

Synonyme: DYT17 antikoerper, DYT18 antikoerper, DYT9 antikoerper, EIG12 antikoerper, GLUT antikoerper, GLUT1 antikoerper, GLUT1DS antikoerper, HTLVR antikoerper, PED antikoerper, wu:fb48e03 antikoerper, wu:fb58d08 antikoerper, zgc:66001 antikoerper, zgc:85785 antikoerper, CTH antikoerper, 0610010I13Rik antikoerper, AI314617 antikoerper, BC019483 antikoerper, CSE antikoerper, Cys3 antikoerper, cysA antikoerper, SCQ11.03c antikoerper, DDBDRAFT_0190313 antikoerper, DDBDRAFT_0191318 antikoerper, DDB_0190313 antikoerper, DDB_0191318 antikoerper, H antikoerper, MGC75946 antikoerper, cystathionine gamma-lyase antikoerper, solute carrier family 2 member 1 antikoerper, cystathionase (cystathionine gamma-lyase) antikoerper, cystathionine gamma-lyase L homeolog antikoerper, CTH antikoerper, SLC2A1 antikoerper, cth antikoerper, Cth antikoerper, SCO3920 antikoerper, mlr1566 antikoerper, TA_RS00415 antikoerper, MAP_RS15640 antikoerper, SPO3344 antikoerper, CNN01730 antikoerper, Mmcs_1928 antikoerper, RHA1_RS31820 antikoerper, HNE_1212 antikoerper, MAV_3867 antikoerper, MSMEG_2394 antikoerper, Mvan_2142 antikoerper, SACE_6136 antikoerper, Mflv_4220 antikoerper, cysA antikoerper, cth.L antikoerper

Hintergrund:

Description: Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.

Gene: CTH

Molekulargewicht: 45 kDa

Gen-ID: 1491

UniProt: P32929

Pathways: ER-Nucleus Signaling, Warburg Effekt