anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) Antikörper

Bezeichnung:: anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Antikörper (STAM2)

Auf www.antikoerper-online.de finden Sie aktuell 100 Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 122 Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Produkte verfügbar.

Synonyme:: 1200004O12Rik, 5730456G07Rik, BB145015, Hbp, MGC52950, stam2, STAM2A, STAM2B, zgc:103628

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	STAM2	10254	O75886
	STAM2	56324	O88811
	STAM2	311030	Q5XHY7
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Am meisten referenzierte anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Antikörper

Human Polyclonal STAM2 Primary Antibody für ELISA, WB - ABIN251316 : Pandey, Fernandez, Steen, Blagoev, Nielsen, Roche, Mann, Lodish: Identification of a novel immunoreceptor tyrosine-based activation motif-containing molecule, STAM2, by mass spectrometry and its involvement in growth factor and cytokine receptor signaling pathways. in The Journal of biological chemistry 2001 (PubMed)
Show all 2 Pubmed References
Human Polyclonal STAM2 Primary Antibody für IHC, IHC (p) - ABIN4356186 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

Weitere Antikörper gegen Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Interaktionspartner

Human Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) Interaktionspartner

The authors propose a structural organization where the AMSH (zeige STAMBP Antikörper)-SH3 binding motif interacts with the STAM2-SH3 domain (zeige ITSN1 Antikörper) and contributes to the correct positioning of AMSH (zeige STAMBP Antikörper) prior to polyubiquitin (zeige UBB Antikörper) chains' cleavage.
The VHS domain of STAM2 directs AMSH to cleave longer Lys63-linked ubiquitin chains
homologous domain of human Bro1 (zeige HMGCR Antikörper) domain-containing proteins, Alix (zeige PDCD6IP Antikörper) and Brox, binds CHMP4B (zeige CHMP4A Antikörper) but not STAM2, despite their high structural similarity
correlation between the percentage of STAM2-positive cells and mitotic count was statistically significant in Gastrointestinal stromal tumors
The study reports the solution NMR structure of the STAM2-VHS domain in complex with monoubiquitin by means of chemical shift perturbations, spin relaxation, and paramagnetic relaxation enhancements.
the SH3 domain of STAM2 plays versatile roles in the context of ubiquitin mediated receptor sorting
Mice carrying a gene trap insertion in the Stam2 transgene do not reveal phenotype changes; therefore, STAM2 function in the digestive tube remains elusive.
report the interactions of the UIM domain and VHS-UIM construct of STAM2 with monoubiquitin (Ub), Lys (zeige LYZ Antikörper)(48)- and Lys (zeige LYZ Antikörper)(63)-linked diubiquitins.
PTP1B (zeige PTPN1 Antikörper) targets the endosomal sorting machinery; dephosphorylation of regulatory sites on the endosomal sorting complex is required for transport component STAM2
Data suggested that association with hepatocyte growth factor-regulated tyrosine kinase substrate is a prerequisite for STAM2 function in early endosome.

Mouse (Murine) Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) Interaktionspartner

Stam2 is expressed in the nervous tissue, heart, digestive and endocrine system during embryo development.
These results demonstrate that the STAMs are indispensably involved in T-cell development and survival in the thymus through the prevention of apoptosis but are dispensable for the proximal signaling of TCR and cytokine receptors.
STAM (zeige STAM Antikörper) proteins function in a multivalent complex that sorts ubiquitinated proteins into the multivesicular body pathway.
SH3 domains of STAM2 and Grb2 (zeige GRB2 Antikörper) retain the moderate characteristics of recognizing their ligand proteins like other SH3 domains for signal protein (zeige KLK7 Antikörper) binding

Cow (Bovine) Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) Interaktionspartner

The G-102A polymorphism in STAM2 is significantly associated with withers height, heart girth, cannon circumference, chest width, and hip height in Wuchuan Black cattle

Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Alternative names and synonyms associated with Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2)

signal transducing adaptor molecule 2 (STAM2) Antikörper
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (Stam2) Antikörper
signal transducing adaptor molecule 2 (Stam2) Antikörper
signal transducing adaptor molecule 2 S homeolog (stam2.S) Antikörper
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (stam2) Antikörper
signal transducing adaptor molecule 2 (stam2) Antikörper

1200004O12Rik Antikörper
5730456G07Rik Antikörper
BB145015 Antikörper
Hbp Antikörper
MGC52950 Antikörper
stam2 Antikörper
STAM2A Antikörper
STAM2B Antikörper
zgc:103628 Antikörper

Bezeichner auf Proteinebene für STAM2

HSE1 homolog , Hrs-binding protein , STAM-2 , STAM-like protein containing SH3 and ITAM domains 2 , signal transducing adapter molecule 2 , Hrs binding protein , hrs-binding protein , signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 , EAST protein , epidermal growth factor receptor-associated protein with SH3 and TAM domain , signal transducing adaptor molecule 2 , signal transducing adapter molecule 2-like

GENE ID	SPEZIES
10254	Homo sapiens
56324	Mus musculus
311030	Rattus norvegicus
380121	Xenopus laevis
424317	Gallus gallus
459661	Pan troglodytes
476150	Canis lupus familiaris
492497	Danio rerio
538505	Bos taurus
695286	Macaca mulatta
100020075	Monodelphis domestica
100057966	Equus caballus
100222318	Taeniopygia guttata
100351322	Oryctolagus cuniculus
100389794	Callithrix jacchus
100490315	Xenopus (Silurana) tropicalis
100560924	Anolis carolinensis
100484799	Ailuropoda melanoleuca
100727167	Cavia porcellus
100157042	Sus scrofa

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