DUSP5 Produkte
(Dual Specificity Phosphatase 5 (DUSP5))
Kategorien
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008].
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Ausgewählte DUSP5 Kategorien
DUSP5 Antikörper
High quality antibodies with extensive validation data.
DUSP5 ELISA Kits
Reliable ELISA kits for a wide range of species.
DUSP5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DUSP5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN560667
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (4)
Kat. Nr.
ABIN560666
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1713770
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene DUSP5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966429
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955467
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955466
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DUSP5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352138
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3079103
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7398719
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DUSP5 Produkten
: "Down-regulation of dual-specificity phosphatase 5 predicts poor prognosis of patients with prostate cancer." in: International journal of clinical and experimental medicine, Vol. 8, Issue 3, pp. 4186-94, (2015) (PubMed).: "Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats." in: PLoS ONE, Vol. 9, Issue 11, pp. e112878, (2014) (PubMed).
: "DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis." in: Oncogene, Vol. 28, Issue 29, pp. 2667-77, (2009) (PubMed).
: "Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1830-45, (2005) (PubMed).
: "Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53." in: Oncogene, Vol. 22, Issue 36, pp. 5586-91, (2003) (PubMed).
Synonyme und alternative Namen zu DUSP5
dual specificity phosphatase 5 (DUSP5), dual specificity phosphatase 5 (dusp5), dual specificity phosphatase 5 S homeolog (dusp5.S), dual specificity phosphatase 5 (Dusp5), Cpg21, dusp, DUSP, DUSP5, Gm337, hvh3, HVH3, MGC84792, wu:fc03b11, wu:fc86e02Bezeichner auf Proteinebene für DUSP5
- dual specificity protein phosphatase 5-like
- dual specificity phosphatase 5
- dual specificity protein phosphatase 5
- VH1-like phosphatase 3
- dual specificity protein phosphatase hVH3
- serine/threonine specific protein phosphatase
- MAP-kinase phosphatase (cpg21)
- MAP-kinase phosphatase CPG21
- candidate plasticity-related gene 21
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