Cullin 4B Produkte
(Cullin 4B (CUL4B))
Kategorien
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte Cullin 4B Kategorien
Cullin 4B Antikörper
High quality antibodies with extensive validation data.
Cullin 4B Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Cullin 4B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN3187726
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN6139255
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Mouse
Applikation
WB, IHC, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN1490724
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Cullin 4B ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6215470
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Cullin 4B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350769
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3130673
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3091967
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Cullin 4B Produkten
: "Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase." in: Cancer cell, Vol. 18, Issue 4, pp. 329-40, (2010) (PubMed).: "Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks." in: Human molecular genetics, Vol. 19, Issue 7, pp. 1324-34, (2010) (PubMed).
: "Cullins in human intra-uterine growth restriction: expressional and epigenetic alterations." in: Placenta, Vol. 31, Issue 2, pp. 151-7, (2010) (PubMed).
: "A novel nonsense mutation in CUL4B gene in three brothers with X-linked mental retardation syndrome." in: Clinical genetics, Vol. 77, Issue 2, pp. 141-4, (2010) (PubMed).
: "CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation." in: Molecular cell, Vol. 40, Issue 1, pp. 9-21, (2010) (PubMed).
: "Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, ..." in: American journal of human genetics, Vol. 80, Issue 2, pp. 345-52, (2007) (PubMed).
: "Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation." in: American journal of human genetics, Vol. 80, Issue 3, pp. 561-6, (2007) (PubMed).
: "Dioxin receptor is a ligand-dependent E3 ubiquitin ligase." in: Nature, Vol. 446, Issue 7135, pp. 562-6, (2007) (PubMed).
Synonyme und alternative Namen zu Cullin 4B
cullin 4B (CUL4B), cullin 4B (Cul4b), cullin 4B (cul4b), cullin 4B S homeolog (cul4b.S), cullin 4B (Tb927.3.1290), 2700050M05Rik, AA409770, CUL-4B, im:7140950, im:7150765, MGC115611, mKIAA0695, MRXHF2, mrxhf2, MRXS15, MRXSC, mrxsc, RGD1564494, SFM2, sfm2, Tb03.1J15.620Bezeichner auf Proteinebene für Cullin 4B
- CUL-4B
- cullin-4B
- cullin 4B
- cullin-4B-like
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