Cullin 2 Produkte
(Cullin 2 (CUL2))
Kategorien
Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte Cullin 2 Kategorien
Cullin 2 Antikörper
High quality antibodies with extensive validation data.
Cullin 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Cullin 2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Cullin 2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN6261115
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Mouse, Rat
Applikation
WB, IHC, IF, IP
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN968173
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7184770
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Cullin 2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381060
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Cullin 2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350758
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350760
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3137093
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Cullin 2 Produkten
: "Twist1 Regulates Vimentin through Cul2 Circular RNA to Promote EMT in Hepatocellular Carcinoma." in: Cancer research, Vol. 78, Issue 15, pp. 4150-4162, (2018) (PubMed).: "KIF5B gene sequence variation and response of cardiac stroke volume to regular exercise." in: Physiological genomics, Vol. 36, Issue 2, pp. 79-88, (2009) (PubMed).
: "TBP-interacting protein 120B (TIP120B)/cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 12, pp. 9017-28, (2007) (PubMed).
: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).
: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).
: "CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans." in: Nature cell biology, Vol. 1, Issue 8, pp. 486-92, (2000) (PubMed).
: "Genomic organization and chromosomal localization of the human CUL2 gene and the role of von Hippel-Lindau tumor suppressor-binding protein (CUL2 and VBP1) mutation and loss in renal-cell carcinoma ..." in: Genes, chromosomes & cancer, Vol. 26, Issue 1, pp. 20-8, (1999) (PubMed).
: "Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 9, Issue 6, pp. 435-49, (1998) (PubMed).
: "The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 6, pp. 2156-61, (1997) (PubMed).
: "cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family." in: Cell, Vol. 85, Issue 6, pp. 829-39, (1996) (PubMed).
Synonyme und alternative Namen zu Cullin 2
cullin 2 (cul2), cullin 2 (CUL2), cullin-2 (PTRG_05231), putative cullin-2 (cul-2) (Smp_079740), cullin-2 (LOC100550749), cullin 2 (Cul2), cullin 2 L homeolog (cul2.L), Cullin-2 (cul-2), 1300003D18Rik, 4932411N15Rik, AI327301, ATCUL2, cul2, Cullin-2, cullin-2, cullin 2, F22D16.2, F22D16_2, fj48a06, LOC100221330, mKIAA4106, wu:fj48a06Bezeichner auf Proteinebene für Cullin 2
- Cullin-2
- CUL-2
- cullin-2
- cullin-2 (cul-2)
- cullin 2
- cullin-2-like
Sie sind hier:
