COMP Proteine
(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
Ergebnisse filtern:
21 Treffer
Produktnummer ABIN7583901
1.842,50 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 58 bis 70 Werktagen
Aktuelle Publikationen für unsere COMP Proteine
: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).
Aliase für COMP Proteine
cartilage oligomeric matrix protein (COMP) Proteinecartilage oligomeric matrix protein (sce3551) Proteine
cartilage oligomeric matrix protein (CJA_1292) Proteine
cartilage oligomeric matrix protein (Comp) Proteine
COMP Proteine
EDM1 Proteine
EPD1 Proteine
MED Proteine
PSACH Proteine
THBS5 Proteine
TSP5 Proteine
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