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anti-Human DNAJC2 Antikörper:
anti-Mouse (Murine) DNAJC2 Antikörper:
anti-Rat (Rattus) DNAJC2 Antikörper:
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Human Polyclonal DNAJC2 Primary Antibody für WB - ABIN611292
Brocke, Chiang, Wagner, Schulman: Functional implications of the subunit composition of neuronal CaM kinase II. in The Journal of biological chemistry 1999
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Human Polyclonal DNAJC2 Primary Antibody für ICC, IF - ABIN4305618
de Brito, Giovanelli, Egal, Sánchez-Romero, Nascimento, Martins, Tincani, Del Negro, Gondak, Almeida, Kowalski, Altemani, Mariano: Loss of expression of Plag1 in malignant transformation from pleomorphic adenoma to carcinoma ex pleomorphic adenoma. in Human pathology 2016
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Human Polyclonal DNAJC2 Primary Antibody für IP, WB - ABIN4305619
Chitale, Richly: DICER and ZRF1 contribute to chromatin decondensation during nucleotide excision repair. in Nucleic acids research 2017
These findings suggest that ZRF1 plays a crucial role in tumor malignant potential through its overexpression and highlight its usefulness as a prognostic factor and potential therapeutic target in gastric cancer
Unexplored functions of ZRF1-mediated remodeling in replication and double strand break repair are discussed.
In response to UV irradiation, DICER (zeige DICER1 Antikörper) is recruited to chromatin in a ZRF1-mediated manner. The H2A-ubiquitin binding protein ZRF1 and DICER (zeige DICER1 Antikörper) together impact on the chromatin conformation via PARP1 (zeige PARP1 Antikörper).
ZRF1 mediates remodeling of this E3 ligase complex directly at the DNA lesion site.
The antibody response to ZRF1 was higher in sera of patients with invasive ductal carcinoma than in sera of patients with other histological types of breast tumors.
Zrf1 is transcriptional regulator of neural fate downstream of Id1 (zeige ID1 Antikörper) in embryonic stem cells.During embryonic stem cell differentiation, Id1 (zeige ID1 Antikörper) levels decrease allowing Zrf1 to activate neural genes.
our data reveal that ZRF1 is a key transcriptional regulator in leukemia progression
Zrf1 plays an essential role in neural progenitor cell generation and maintenance
ZRF1 regulates the INK4-ARF locus during cellular proliferation and senescence, and alterations in ZRF1 may contribute to tumorigenesis.
the majority of AML (zeige RUNX1 Antikörper) patients elicited a humoral immune response against the tumor antigen MPP11 (zeige PMPCB Antikörper)
These findings reveal a mechanism by which nutrient sensing pathways impact on cell senescence through the activation of mTORC1-S6 kinases and the phosphorylation of ZRF1.
Zrf1 is identified as a novel regulator of the mesodermal lineage that might facilitate spatiotemporal expression of genes.
Data suggest involvement of MIDA1 in the stimulation of transcription in concert with Hsp70/Hsc70 molecular chaperones.
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
dnaJ homolog subfamily C member 2
, zuotin related factor 1
, M-phase phosphoprotein 11
, zuotin-related factor 1
, Id associate 1
, zuotin related factor 2
, (rat homolog) mouse id-associated protein 1
, gliosarcoma-related antigen MIDA1