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anti-Mouse (Murine) Occludin Antikörper:
anti-Rat (Rattus) Occludin Antikörper:
anti-Human Occludin Antikörper:
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Human Polyclonal Occludin Primary Antibody für IF (p), IHC (p) - ABIN687337
Gu, Xue, Wei, Zhang, Li: Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats. in Neuroscience letters 2011
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Human Polyclonal Occludin Primary Antibody für ELISA, ICC - ABIN6263796
Zou, Xiang, Wang, Peng, Wei: Oregano Essential Oil Improves Intestinal Morphology and Expression of Tight Junction Proteins Associated with Modulation of Selected Intestinal Bacteria and Immune Status in a Pig Model. in BioMed research international 2017
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Human Polyclonal Occludin Primary Antibody für ICC, IF - ABIN4341293
Liu, Schrott-Fischer, Glueckert, Benav, Rask-Andersen: The Human "Cochlear Battery" - Claudin-11 Barrier and Ion Transport Proteins in the Lateral Wall of the Cochlea. in Frontiers in molecular neuroscience 1970
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Human Polyclonal Occludin Primary Antibody für IHC (fro), IF - ABIN2192203
Van Itallie, Anderson: Occludin confers adhesiveness when expressed in fibroblasts. in Journal of cell science 1997
Cow (Bovine) Polyclonal Occludin Primary Antibody für WB - ABIN2775620
Shen, Weber, Turner: The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. in The Journal of cell biology 2008
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Dog (Canine) Monoclonal Occludin Primary Antibody für ELISA, IF - ABIN337048
Krueger, Härtig, Reichenbach, Bechmann, Michalski: Blood-brain barrier breakdown after embolic stroke in rats occurs without ultrastructural evidence for disrupting tight junctions. in PLoS ONE 2013
Human Polyclonal Occludin Primary Antibody für ELISA, ICC - ABIN4341292
Liu, Xu, Ji, Liu, Mo, Tollerud, Gu, Zhang: Sublethal effects of zinc oxide nanoparticles on male reproductive cells. in Toxicology in vitro : an international journal published in association with BIBRA 2016
Human Polyclonal Occludin Primary Antibody für ELISA, WB - ABIN1089703
Dong, Singh, Wei, Yao, Wang: Protective Effect of 1,25-Dihydroxy Vitamin D3 on Pepsin-Trypsin-Resistant Gliadin-Induced Tight Junction Injuries. in Digestive diseases and sciences 2018
The C-terminal DSP domain induced phosphorylation of occludin Ser(490) and focal adhesion kinase (FAK) Ser(722) and Tyr(576). Coexpression of DSP, occludin and FAK was detected in dental mesenchymal cells during tooth development. Occludin physically interacts with FAK, and occludin and FAK phosphorylation can be blocked by DSP and occludin antibodies.
Endothelial cellsTLR4 strongly regulates retinal vessel permeability by reducing expression of occludin and zonula occludens 1 (zeige TJP1 Antikörper).
The zinc sensing receptor, ZnR/GPR39 (zeige GPR39 Antikörper), triggers intracellular Ca(2 (zeige CA2 Antikörper)+) signalling in colonocytes thereby inducing occludin expression. Moreover, ZnR/GPR39 (zeige GPR39 Antikörper) is essential for epithelial barrier recovery in the dextran sodium sulfate (DSS (zeige PMP22 Antikörper)) ulcerative colitis model.
Occludin expression by epidermal gammadelta T cells upon activation in response to epidermal stress allows them to move, which could be important for augmentation of immune responses via collaboration with other cells.
Intracellular zinc has an essential role in the maintenance of the intestinal epithelial tight junction barrier through regulation of occludin proteolysis and claudin-3 (zeige CLDN3 Antikörper) transcription.
miR (zeige MLXIP Antikörper)-429 could down-regulate the expression of Ocln by targeting the Ocln 3'-UTR (zeige UTS2R Antikörper), which impaired intestinal barrier function in diabetes mellitus mice.
STAT3 (zeige STAT3 Antikörper) activation downregulates the ZO-1 (zeige TJP1 Antikörper) and occludin levels and increases the endothelial permeability through the induction of VEGF (zeige VEGFA Antikörper) production in retinal endothelial cells.
Tricellulin (zeige MARVELD2 Antikörper) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.
These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.
occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.
ZO-1 (zeige TJP1 Antikörper) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.
ADMA has potent adverse effects on cell proliferation, intracellular ROS (zeige ROS1 Antikörper) generation, cell permeability, levels of ICAM-1 (zeige ICAM1 Antikörper), and the tight-junction protein occludin
the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades
cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (zeige TJP1 Antikörper) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
These data demonstrate a novel mechanism of VEGF (zeige VEGFA Antikörper)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.
our findings for the first time identify the role of occludin as a tumor promoter and a prometastatic factor in lung cancer, demonstrating that occludin is a potential prognostic biomarker and therapeutic target in lung cancer
Occludin protein may contribute to the development of cervical cancer. However, it was not correlated with the clinical features.
Low occludin expression is associated with Renal cell carcinoma (zeige MOK Antikörper).
decreased interaction between ZO-1 (zeige TJP1 Antikörper) and occludin might contribute to the epiphora occurred in the transplanted submandibular glands
integration of claudin-2 (zeige CLDN2 Antikörper), occludin and ZO-1 (zeige TJP1 Antikörper) is necessary for maintaining the function of the proximal tubular epithelium.
Molecular studies of the OCLN gene (NM_001205254) identified six distinct candidate mutations in polymicrogyria.
Glutamine (zeige GFPT1 Antikörper) increased claudin-1 (zeige CLDN7 Antikörper) expression in the colonic mucosa of patients with irritable bowel syndrome. In contrast, occludin expression was not significantly modified by glutamine (zeige GFPT1 Antikörper).
Viral infectivity was significantly reduced by miR (zeige MLXIP Antikörper)-200c but enhanced by miR (zeige MLXIP Antikörper)-122.
The mechanism of transition from nondifferentiated to differentiated states in HepaRG cells was studed by proteomics. Two key factors (MMP-14 (zeige MMP14 Antikörper) and OCLN) were validated by qRT-PCR and Western blot.
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
, tight-junction protein
, thiopurine methyltransferase
, tight junction protein occludin