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BIN1 Proteine

(Bridging Integrator 1 (BIN1))
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Sep 2011].

9 Treffer

BIN1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Independent Validation 1 Validierung
Produktnummer ABIN2715270
Independently Validated
BIN1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Produktnummer ABIN1346679
 
BIN1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS – PAGE SDS
Produktnummer ABIN667182
 
BIN1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA
Produktnummer ABIN7575169
 
BIN1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Produktnummer ABIN7399799
 
BIN1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
Produktnummer ABIN2128154
 
BIN1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715269
 
BIN1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715268
 
BIN1 Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7583651
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Antibody Production (AbP)
    • ELISA
    • Standard (STD)
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunogen (Imm)
    • Positive Control (PC)
  • Reaktivität
    • Human
    • Rat
  • Abbildungen verfügbar
  • Independent Validation
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • Bindungsspezifität
    • AA 1-439
    • AA 1-276
    • AA 2-588
    • Transcript Variant 2
    • Transcript Variant 8
    • Transcript Variant 9
  • Konjugat
    • His tag
    • Myc-DYKDDDDK Tag
    • GST tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Hersteller
    • antibodies-online
    • OriGene
    • CUSABIO

Aliase für BIN1 Proteine

bridging integrator 1 (BIN1) Proteine
bridging integrator 1 S homeolog (bin1.S) Proteine
bridging integrator 1 (bin1) Proteine
bridging integrator 1b (bin1b) Proteine
bridging integrator 1 (Bin1) Proteine
ALP-1 Proteine
amph2 Proteine
AMPH2 Proteine
amphl Proteine
AMPHL Proteine
Amphl Proteine
bin1 Proteine
BIN1 Proteine
BRAMP-2 Proteine
cb57 Proteine
MGC53185 Proteine
MGC76187 Proteine
sh3p9 Proteine
SH3P9 Proteine
zgc:86701 Proteine
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