ATP2B2 Produkte
(ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))
Kategorien
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Ausgewählte ATP2B2 Kategorien
ATP2B2 Antikörper
High quality antibodies with extensive validation data.
ATP2B2 ELISA Kits
Reliable ELISA kits for a wide range of species.
ATP2B2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ATP2B2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7436264
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN1385852
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, ELISA, IF
Validierungen
- (2)
Kat. Nr.
ABIN7163515
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ATP2B2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953996
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5674663
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN2541838
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ATP2B2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7552398
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7565176
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7408519
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ATP2B2 Produkten
: "Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance." in: Neuron, Vol. 96, Issue 4, pp. 827-838.e9, (2017) (PubMed).: "Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease." in: Molecular psychiatry, (2016) (PubMed).
: "Disrupted calcium homeostasis is involved in elevated zinc ion-induced photoreceptor cell death." in: Archives of biochemistry and biophysics, Vol. 560, pp. 44-51, (2014) (PubMed).
: "Zinc oxide nanoparticles decrease the expression and activity of plasma membrane calcium ATPase, disrupt the intracellular calcium homeostasis in rat retinal ganglion cells." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1849-59, (2013) (PubMed).
: "Plasma membrane Ca2+ pump in rat brain. Patterns of alternative splices seen by isoform-specific antibodies." in: The Journal of biological chemistry, Vol. 272, Issue 38, pp. 23741-7, (1997) (PubMed).
: "Cloning and expression of isoform 2 of the human plasma membrane Ca2+ ATPase. Functional properties of the enzyme and its splicing products." in: The Journal of biological chemistry, Vol. 269, Issue 42, pp. 26178-83, (1994) (PubMed).
: "Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25993-6003, (1994) (PubMed).
: "Molecular cloning of two isoforms of the plasma membrane Ca2+-transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases." in: The Journal of biological chemistry, Vol. 263, Issue 18, pp. 8646-57, (1988) (PubMed).
Synonyme und alternative Namen zu ATP2B2
ATPase plasma membrane Ca2+ transporting 2 (ATP2B2), ATPase, Ca++ transporting, plasma membrane 2 (Atp2b2), ATPase plasma membrane Ca2+ transporting 2 (Atp2b2), ATPase, Ca++ transporting, plasma membrane 2 (atp2b2), ATPase plasma membrane Ca2+ transporting 2 (atp2b2), ATP2B2, ATP2B4, D6Abb2e, dfw, jog, PMCA, PMCA2, PMCA2a, PMCA2i, Tmy, wms, wriBezeichner auf Proteinebene für ATP2B2
- plasma membrane Ca(2+)-ATPase
- plasma membrane Ca2+ pump 2
- plasma membrane calcium ATPase
- plasma membrane calcium pump
- plasma membrane calcium-transporting ATPase 2
- ATPase, Ca++ transporting, plasma membrane 4
- plasma membrane calcium ATPase 2
- ATPase, Ca++ transporting, plasma membrane 2
- plasma membrane calcium-transporting ATPase 4
- deaf waddler
- wriggle
- ATPase isoform 2 Na+K+ transporting beta polypeptide 2
- ATPase isoform 2, Na+K+ transporting, beta polypeptide 2
- plasma membrane Ca++-ATPase
- pmca2
- plasma membrane calcium-transporting ATPase 2-like
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