anti-DFFA (DFFA) Antikörper

Bezeichnung:: anti-DNA Fragmentation Factor, 45kDa, alpha Polypeptide Antikörper (DFFA)

Auf www.antikoerper-online.de finden Sie aktuell 230 DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) Antikörper von 0 unterschiedlichen Herstellern. Insgesamt sind aktuell 266 DFFA Produkte verfügbar.

Synonyme:: A330085O09Rik, DFF-45, DFF1, DFF35, Dff45, DFFA, ICAD, ICAD-L, ICAD-S, zgc:92229

Alle Antikörper anzeigen	Gen	GeneID	UniProt
Anti-Human DFFA	DFFA	1676	O00273
Anti-Maus DFFA	DFFA	13347	O54786
Anti-Ratte DFFA	DFFA	114214
Weitere Synonyme anzeigen

Verknüpfte Pathways mit anti-DFFA Antikörper

Weitere Produktkategorien zu DFFA Antikörper

Am meisten referenzierte anti-DFFA Antikörper

Human Polyclonal DFFA Primary Antibody für ELISA, ICC - ABIN4305087 : Nagata, Kishi, Liu, Matsuda, Imanaka, Tsukada, Kang, Muraguchi: The regulation of DNAse activities in subcellular compartments of activated thymocytes. in Immunology 2002 (PubMed)
Mouse (Murine) Polyclonal DFFA Primary Antibody für WB - ABIN222902 : Boulares, Zoltoski, Yakovlev, Xu, Smulson: Roles of DNA fragmentation factor and poly(ADP-ribose) polymerase in an amplification phase of tumor necrosis factor-induced apoptosis. in The Journal of biological chemistry 2001 (PubMed)

Weitere Antikörper gegen DFFA Interaktionspartner

Human DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) Interaktionspartner

evaluate the relative expression levels of miR (zeige MLXIP Antikörper)-196a2 and three of its selected apoptosis-related targets; ANXA1 (zeige ANXA1 Antikörper), DFFA and PDCD4 (zeige PDCD4 Antikörper) in a sample of GI cancer patients
Data show that the caspase-activated DNase (CAD (zeige DFFB Antikörper)) is activated when caspases cleave its endogenous inhibitor ICAD, resulting in the characteristic DNA laddering of apoptosis.
Data suggest that DFF45 gene silencing, when applied in combination with doxorubicin, may offer a therapeutic strategy for the treatment of breast cancer.
ICAD deficiency was associated with severe genomic instability.
mRNA splicing is actively driven toward the pro-apoptotic isoforms of Bim (zeige BCL2L11 Antikörper), Bcl-x (zeige BCL2L1 Antikörper), and ICAD in Pnn (zeige PNN Antikörper)-depleted MCF-7 cells.
The DFF45 level in human endometrium corresponds to the respective phase of the menstrual cycle and decreases significantly after menopause.
study reveals a previously unrecognized function of miR (zeige MLXIP Antikörper)-145 in DFF45 processing, which may underlie crucial aspects of cancer biology
The heterodimer, DFF40 (zeige DFFB Antikörper)-DFF45, is localized to the chromatin fraction under apoptotic as well as non-apoptotic conditions.
DFF45 at chromosome 1 reveal rare allelic variants in neuroblastoma (zeige ARHGEF16 Antikörper) tumors
NMR solution structure of the C-terminal domain of DFF45, which is essential for its chaperone-like activity

Mouse (Murine) DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) Interaktionspartner

Co-transfection of mouse DFF45(-/-) fibroblasts with plasmids encoding human DFF40 (zeige DFFB Antikörper) and DFF45 reversed the apoptosis resistance normally observed in these cells
a lack of DFF45 facilitates hippocampus-dependent nonspatial memory, as well as hippocampus-dependent spatial memory
apoptotic DNA fragmentation factor is required for the maintenance of genetic stability and may play a role in tumor suppression

DFFA Antigen-Profil

Beschreibung des Gens

Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with DFFA

DNA fragmentation factor subunit alpha (DFFA) Antikörper
DNA fragmentation factor, alpha subunit (Dffa) Antikörper
DNA fragmentation factor, 45kDa, alpha polypeptide (dffa) Antikörper
DNA fragmentation factor subunit alpha (Dffa) Antikörper
DNA fragmentation factor, alpha polypeptide (dffa) Antikörper

A330085O09Rik Antikörper
DFF-45 Antikörper
DFF1 Antikörper
DFF35 Antikörper
Dff45 Antikörper
DFFA Antikörper
ICAD Antikörper
ICAD-L Antikörper
ICAD-S Antikörper
zgc:92229 Antikörper

Bezeichner auf Proteinebene für DFFA

DFF45 , DNA fragmentation factor 45 kDa subunit , DNA fragmentation factor subunit alpha , inhibitor of CAD , DFF-45 , DNA fragmentation factor, 45kDa, alpha polypeptide

GENE ID	SPEZIES
1676	Homo sapiens
13347	Mus musculus
487449	Canis lupus familiaris
419451	Gallus gallus
457928	Pan troglodytes
507981	Bos taurus
548407	Xenopus (Silurana) tropicalis
713544	Macaca mulatta
100173283	Pongo abelii
114214	Rattus norvegicus
100719233	Cavia porcellus
436904	Danio rerio

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Show all anti-DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) Antikörper with Pubmed References

Human DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) Interaktionspartner

Mouse (Murine) DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with DFFA

Bezeichner auf Proteinebene für DFFA