APOE Produkte
(Apolipoprotein E (APOE))
Kategorien
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008].
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Ausgewählte APOE Kategorien
APOE Antikörper
High quality antibodies with extensive validation data.
APOE ELISA Kits
Reliable ELISA kits for a wide range of species.
APOE Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene APOE Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (9)
Kat. Nr.
ABIN7429133
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (9)
Kat. Nr.
ABIN7429139
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Dog
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7440422
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene APOE ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
- (1)
Kat. Nr.
ABIN612665
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Competition ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6975758
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Competition ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6974557
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene APOE Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7273868
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7273871
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7273869
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren APOE Produkten
: "Isoform- and cell-state-specific lipidation of ApoE in astrocytes." in: Cell reports, Vol. 38, Issue 9, pp. 110435, (2022) (PubMed).: "Hepatic HuR modulates lipid homeostasis in response to high-fat diet." in: Nature communications, Vol. 11, Issue 1, pp. 3067, (2020) (PubMed).
: "Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects." in: The Journal of allergy and clinical immunology, Vol. 144, Issue 2, pp. 426-441.e3, (2020) (PubMed).
: "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line." in: Stem cell research, Vol. 34, pp. 101349, (2019) (PubMed).
: "APOE ε2 is associated with increased tau pathology in primary tauopathy. ..." in: Nature communications, Vol. 9, Issue 1, pp. 4388, (2019) (PubMed).
: "Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7." in: EBioMedicine, Vol. 36, pp. 29-38, (2019) (PubMed).
: "Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species." in: Journal of the American Society of Nephrology : JASN, Vol. 30, Issue 5, pp. 767-781, (2019) (PubMed).
: "Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 8, pp. e145-e158, (2019) (PubMed).
: "Evaluation of α-synuclein and apolipoprotein E as potential biomarkers in cerebrospinal fluid to monitor pharmacotherapeutic efficacy in dopamine dictated disease states of Parkinson's disease and ..." in: Neuropsychiatric disease and treatment, Vol. 15, pp. 2073-2085, (2019) (PubMed).
: "Hypolipidemic and anti-inflammatory effects of aorta and heart tissues of cattle and pigs in the atherosclerosis rat model." in: Animal science journal = Nihon chikusan Gakkaihō, Vol. 89, Issue 5, pp. 784-793, (2018) (PubMed).
Synonyme und alternative Namen zu APOE
apolipoprotein E (apoe), apolipoprotein Ea (apoea), apolipoprotein E (Apoe), apolipoprotein E (APOE), ad2, AD2, AI255918, Apo-E, apoe, APOEA, apoprotein, im:7036787, LDLCQ5, LPG, wu:fb69a05, zgc:110064Bezeichner auf Proteinebene für APOE
- apolipoprotein E
- ApoE-1
- apo-E
- apolipoprotein E3
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