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APOBEC3H Produkte

(Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H))

Kategorien

This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009].

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Ausgewählte APOBEC3H Kategorien

APOBEC3H Antikörper

High quality antibodies with extensive validation data.

APOBEC3H Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene APOBEC3H Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN531149
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6259988
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Monkey
Applikation WB
Validierungen
Kat. Nr. ABIN6749340
Menge 100 μL
Datenblatt Datenblatt

Empfohlene APOBEC3H Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345363
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3087960
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Rhesus Monkey
Source Yeast
Validierungen
Kat. Nr. ABIN1620112
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren APOBEC3H Produkten

Ebrahimi, Richards, Carpenter, Wang, Ikeda, Becker, Cheng, McCann, Shaban, Salamango, Starrett, Lingappa, Yong, Brown, Harris: "Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease." in: Nature communications, Vol. 9, Issue 1, pp. 4137, (2019) (PubMed).

Wang, Becker, Shi, Lauer, Salamango, Aihara, Shaban, Harris: "The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H." in: Journal of molecular biology, Vol. 431, Issue 24, pp. 5019-5031, (2019) (PubMed).

Salamango, Becker, McCann, Cheng, Demir, Amaro, Brown, Shaban, Harris: "APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction." in: Molecular and cellular biology, Vol. 38, Issue 23, (2018) (PubMed).

Starrett, Luengas, McCann, Ebrahimi, Temiz, Love, Feng, Adolph, Chelico, Law, Carpenter, Harris: "The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis." in: Nature communications, Vol. 7, pp. 12918, (2016) (PubMed).

Ooms, Letko, Simon: "The Structural Interface between HIV-1 Vif and Human APOBEC3H." in: Journal of virology, Vol. 91, Issue 5, (2016) (PubMed).

Refsland, Hultquist, Luengas, Ikeda, Shaban, Law, Brown, Reilly, Emerman, Harris: "Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity." in: PLoS genetics, Vol. 10, Issue 11, pp. e1004761, (2014) (PubMed).

Shaban, Shi, Lauer, Carpenter, Richards, Salamango, Wang, Lopresti, Banerjee, Levin-Klein, Brown, Aihara, Harris: "The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism." in: Molecular cell, Vol. 69, Issue 1, pp. 75-86.e9 (PubMed).

Synonyme und alternative Namen zu APOBEC3H

apolipoprotein B mRNA editing enzyme catalytic subunit 3H (APOBEC3H), A3H, APOBEC3A, ARP10

Bezeichner auf Proteinebene für APOBEC3H

  • APOBEC-related protein 10
  • ARP-10
  • DNA dC->dU-editing enzyme APOBEC-3H
  • apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H
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