SMAD3 Antikörper
Kurzübersicht für SMAD3 Antikörper (ABIN969402)
Target
Alle SMAD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- SMAD3 Antibody
-
Aufreinigung
- Ascitic fluid
-
Immunogen
- Purified recombinant fragment of human SMAD3 expressed in E. Coli.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
-
ELISA: 1/10000
ICC: 1/200 - 1/1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Ascitic fluid containing 0.03 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression." in: The American journal of pathology, Vol. 176, Issue 3, pp. 1139-47, (2010) (PubMed).
: "Association of TGFBR2 polymorphism with risk of sudden cardiac arrest in patients with coronary artery disease." in: Heart rhythm : the official journal of the Heart Rhythm Society, Vol. 6, Issue 12, pp. 1745-50, (2009) (PubMed).
-
: "Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression." in: The American journal of pathology, Vol. 176, Issue 3, pp. 1139-47, (2010) (PubMed).
-
- SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
-
Andere Bezeichnung
- SMAD3
-
Hintergrund
- SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
-
Molekulargewicht
- 48 kDa
-
UniProt
- P84022
-
Pathways
- Zellzyklus, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagie
Target
-