Mammaglobin A Antikörper

Produktnummer ABIN969392

Der Maus Monoklonal Anti-Mammaglobin A-Antikörper wurde für IHC, ELISA, ICC und FACS validiert. Er ist geeignet, Mammaglobin A in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Mammaglobin A Antikörper (ABIN969392)

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Mammaglobin A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: 3C8

Produktdetails anti-Mammaglobin A Antikörper

Verwendungszweck: SCGB2A2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human SCGB2A2 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Mammaglobin A Antikörper (ABIN969392)

Sasaki, Tsunoda, Hatanaka, Mori, Iwata, Yatabe: "Breast-specific expression of MGB1/mammaglobin: an examination of 480 tumors from various organs and clinicopathological analysis of MGB1-positive breast cancers." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 20, Issue 2, pp. 208-14, (2007) (PubMed).

Gargano, Agnese, Calò, Corsale, Augello, Bruno, La Paglia, Gullo, Ottini, Russo, Fulfaro, Rinaldi, Crosta, Cicero, Majorana, Palmeri, Cipolla, Agrusa, Gulotta, Morello, Di Fede, Adamo, Colucci et al.: "Detection and quantification of mammaglobin in the blood of breast cancer patients: can it be useful as a potential clinical marker? Preliminary results of a GOIM (Gruppo Oncologico dell'Italia ..." in: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Vol. 17 Suppl 7, pp. vii41-5, (2006) (PubMed).

Details zu Mammaglobin A

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Andere Bezeichnung: SCGB2A2

Hintergrund: Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.Tissue specificity: Mammary gland specific. Over-expressed in breast cancer.

Molekulargewicht: 11 kDa

UniProt: Q13296