RPS6KA3 Antikörper

Produktnummer ABIN969386

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-RPS6KA3 Antikörper wird verwendet zum Nachweis von RPS6KA3 in Proben von Human. Er wurde validiert für WB, ELISA, FACS und ICC.

Kurzübersicht für RPS6KA3 Antikörper (ABIN969386)

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RPS6KA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 4E10

Produktdetails anti-RPS6KA3 Antikörper

Verwendungszweck: RSK2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human RSK2 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-RPS6KA3 Antikörper (ABIN969386)

Dehan, Bassermann, Guardavaccaro, Vasiliver-Shamis, Cohen, Lowes, Dustin, Huang, Taunton, Pagano: "betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis." in: Molecular cell, Vol. 33, Issue 1, pp. 109-16, (2009) (PubMed).

Cho, Yao, Pugliese, Malakhova, Bode, Dong: "A regulatory mechanism for RSK2 NH(2)-terminal kinase activity." in: Cancer research, Vol. 69, Issue 10, pp. 4398-406, (2009) (PubMed).

Details zu RPS6KA3

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Andere Bezeichnung: RSK2

Hintergrund: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Molekulargewicht: 80 kDa

Gen-ID: 6197

UniProt: P51812

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades