Prostate Specific Antigen Antikörper (AA 26-251)

Produktnummer ABIN969369

Dieses Anti-Prostate Specific Antigen-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Prostate Specific Antigen in ELISA, IHC und FACS. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Prostate Specific Antigen Antikörper (AA 26-251) (ABIN969369)

Target: Prostate Specific Antigen (PSA)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prostate Specific Antigen Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 5A11E2

Produktdetails anti-Prostate Specific Antigen Antikörper

Bindungsspezifität: AA 26-251

Verwendungszweck: PSA (KLK3) Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of KLK3 (aa26-251) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Prostate Specific Antigen Antikörper (ABIN969369)

Alzghoul, Hailat, Zivanovic, Que, Shah: "Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip." in: Biosensors & bioelectronics, Vol. 77, pp. 491-8, (2015) (PubMed).

Hassan, Kumar, Singh, Yadav: "Structural model of human PSA: a target for prostate cancer therapy." in: Chemical biology & drug design, Vol. 70, Issue 3, pp. 261-7, (2007) (PubMed).

Details zu Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Andere Bezeichnung: PSA (KLK3)

Hintergrund: Kallikrein-related peptidase 3.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Gen-ID: 354

UniProt: P07288

Pathways: Komplementsystem