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c-MYC Antikörper

Dieses Anti-c-MYC-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von c-MYC in ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.
Produktnummer ABIN969300

Kurzübersicht für c-MYC Antikörper (ABIN969300)

Target

Alle c-MYC (MYC) Antikörper anzeigen
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reaktivität

  • 386
  • 167
  • 118
  • 15
  • 15
  • 15
  • 15
  • 13
  • 11
  • 9
  • 9
  • 6
  • 6
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 291
  • 117
  • 7
  • 5
  • 3
  • 1
  • 1
Maus

Klonalität

  • 267
  • 157
Monoklonal

Konjugat

  • 209
  • 32
  • 24
  • 22
  • 8
  • 7
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser c-MYC Antikörper ist unkonjugiert

Applikation

  • 294
  • 147
  • 110
  • 99
  • 84
  • 64
  • 58
  • 31
  • 28
  • 26
  • 18
  • 14
  • 13
  • 12
  • 11
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA

Klon

7E10
  • Verwendungszweck

    MYC Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human MYC expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Fang, Liu, Wu, Liu, Pan, Li: "Upregulation of long noncoding RNA CCAT1-L promotes epithelial-mesenchymal transition in gastric adenocarcinoma." in: OncoTargets and therapy, Vol. 11, pp. 5647-5655, (2018) (PubMed).

    Zhang, Zeng, Jiao, Li, Liu, Zhang, Yang: "AA28-67 domain within MyD88 suppresses c-myc activity and expression to regulate differentiation and function of dendritic cells." in: Clinical immunology (Orlando, Fla.), Vol. 133, Issue 3, pp. 324-32, (2009) (PubMed).

    Lal, Navarro, Maher, Maliszewski, Yan, ODay, Chowdhury, Dykxhoorn, Tsai, Hofmann, Becker, Gorospe, Hide, Lieberman: "miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements." in: Molecular cell, Vol. 35, Issue 5, pp. 610-25, (2009) (PubMed).

  • Target

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    Andere Bezeichnung

    MYC

    Hintergrund

    The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).

    Molekulargewicht

    49 kDa

    UniProt

    P01106

    Pathways

    p53 Signalweg, Zellzyklus, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effekt
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