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c-MYC Antikörper

MYC Reaktivität: Human ELISA Wirt: Maus Monoclonal 7E10 unconjugated
Produktnummer ABIN969300
  • Target Alle c-MYC (MYC) Antikörper anzeigen
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Reaktivität
    • 361
    • 167
    • 118
    • 15
    • 15
    • 13
    • 13
    • 13
    • 11
    • 9
    • 9
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 281
    • 102
    • 7
    • 5
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 267
    • 132
    Monoklonal
    Konjugat
    • 205
    • 30
    • 24
    • 22
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser c-MYC Antikörper ist unkonjugiert
    Applikation
    • 293
    • 147
    • 97
    • 88
    • 84
    • 63
    • 58
    • 31
    • 28
    • 26
    • 18
    • 14
    • 12
    • 11
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA
    Verwendungszweck
    MYC Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human MYC expressed in E. Coli.
    Klon
    7E10
    Isotyp
    IgG1
    Top Product
    Discover our top product MYC Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Fang, Liu, Wu, Liu, Pan, Li: "Upregulation of long noncoding RNA CCAT1-L promotes epithelial-mesenchymal transition in gastric adenocarcinoma." in: OncoTargets and therapy, Vol. 11, pp. 5647-5655, (2018) (PubMed).

    Zhang, Zeng, Jiao, Li, Liu, Zhang, Yang: "AA28-67 domain within MyD88 suppresses c-myc activity and expression to regulate differentiation and function of dendritic cells." in: Clinical immunology (Orlando, Fla.), Vol. 133, Issue 3, pp. 324-32, (2009) (PubMed).

    Lal, Navarro, Maher, Maliszewski, Yan, ODay, Chowdhury, Dykxhoorn, Tsai, Hofmann, Becker, Gorospe, Hide, Lieberman: "miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements." in: Molecular cell, Vol. 35, Issue 5, pp. 610-25, (2009) (PubMed).

  • Target
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Andere Bezeichnung
    MYC (MYC Produkte)
    Hintergrund
    The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).
    Molekulargewicht
    49 kDa
    UniProt
    P01106
    Pathways
    p53 Signalweg, Zellzyklus, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effekt
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