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c-MYC Antikörper
MYC
Reaktivität: Human
ELISA
Wirt: Maus
Monoclonal
7E10
unconjugated
Produktdetails anti-c-MYC Antikörper
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Target
Alle c-MYC (MYC) Antikörper anzeigen
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Reaktivität
Alle Reaktivitäten für c-MYC Antikörper
Human
Wirt
Alle Wirte für c-MYC Antikörper
Maus
Klonalität
Alle Klonalitäten für c-MYC Antikörper
Monoklonal
Konjugat
Alle Konjugate für c-MYC Antikörper
Dieser c-MYC Antikörper ist unkonjugiert
Applikation
Alle Applikationen für c-MYC Antikörper
ELISA
Verwendungszweck
MYC Antibody
Aufreinigung
Ascitic fluid
Immunogen
Purified recombinant fragment of human MYC expressed in E. Coli.
Klon
7E10
Isotyp
IgG1
Top Product
Discover our top product MYC Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Referenzen für anti-c-MYC Antikörper (ABIN969300)
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Fang, Liu, Wu, Liu, Pan, Li : "Upregulation of long noncoding RNA CCAT1-L promotes epithelial-mesenchymal transition in gastric adenocarcinoma. " in: OncoTargets and therapy , Vol. 11 , pp. 5647-5655 , (2018 ) (PubMed ).
Zhang, Zeng, Jiao, Li, Liu, Zhang, Yang : "AA28-67 domain within MyD88 suppresses c-myc activity and expression to regulate differentiation and function of dendritic cells. " in: Clinical immunology (Orlando, Fla.) , Vol. 133 , Issue 3 , pp. 324-32 , (2009 ) (PubMed ).
Lal, Navarro, Maher, Maliszewski, Yan, ODay, Chowdhury, Dykxhoorn, Tsai, Hofmann, Becker, Gorospe, Hide, Lieberman : "miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. " in: Molecular cell , Vol. 35 , Issue 5 , pp. 610-25 , (2009 ) (PubMed ).
Details zu c-MYC
(ausblenden)
Target
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Andere Bezeichnung
MYC (MYC Produkte )
Hintergrund
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).
Molekulargewicht
49 kDa
UniProt
P01106
Pathways
p53 Signalweg , Zellzyklus , Sensory Perception of Sound , Transition Metal Ion Homeostasis , Mitotic G1-G1/S Phases , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Positive Regulation of Response to DNA Damage Stimulus , Warburg Effekt
Zuletzt angesehen
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