MSH6 Antikörper
(1 reference)Kurzübersicht für MSH6 Antikörper (ABIN969293)
Target
Alle MSH6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- MSH6 Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human MSH6 expressed in E. Coli.
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Isotyp
- IgG2a
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anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibody
MSH6 Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 7D9H5 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 2E3A10 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 217-395) antibodyMSH6 Reaktivität: Human, Maus, Affe WB, ELISA, FACS Wirt: Maus Monoclonal 1D1C2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 931-1030) antibodyMSH6 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 1F2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reaktivität: Human WB, ELISA, IHC, IF, Coat, StM Wirt: Maus Monoclonal MSH6-3091 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (N-Term) antibodyMSH6 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) antibodyMSH6 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5B11 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (Internal Region) antibodyMSH6 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 225-333) antibodyMSH6 Reaktivität: Human, Maus, Ratte, Hund WB, IF Wirt: Maus Monoclonal 44-MSH6 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1-400) antibodyMSH6 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Germ-line mutations in mismatch repair genes associated with prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2460-7, (2009) (PubMed).
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: "Germ-line mutations in mismatch repair genes associated with prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2460-7, (2009) (PubMed).
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- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Andere Bezeichnung
- MSH6
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Hintergrund
- This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.
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Molekulargewicht
- 160 kDa
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Gen-ID
- 2956
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UniProt
- P52701
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Pathways
- DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
Target
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