Fibronectin 1 Antikörper

Produktnummer ABIN969149

Der Maus Monoklonal Anti-Fibronectin 1-Antikörper wurde für ELISA, IHC und FACS validiert. Er ist geeignet, Fibronectin 1 in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für Fibronectin 1 Antikörper (ABIN969149)

Target: Fibronectin 1 (FN1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibronectin 1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 2F4

Produktdetails anti-Fibronectin 1 Antikörper

Verwendungszweck: FN1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human FN1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Fibronectin 1 Antikörper (ABIN969149)

Li, Li, Duan, Cai, You, Zhou, Yang, Tuo, Liu: "Blockage of TGF-α Induced by Spherical Silica Nanoparticles Inhibits Epithelial-Mesenchymal Transition and Proliferation of Human Lung Epithelial Cells." in: BioMed research international, Vol. 2019, pp. 8231267, (2019) (PubMed).

Guo, You, Li, Tuo, Liu: "Spherical silica nanoparticles promote malignant transformation of BEAS-2B cells by stromal cell-derived factor-1α (SDF-1α)." in: The Journal of international medical research, Vol. 47, Issue 3, pp. 1264-1278, (2019) (PubMed).

Ryschich, Khamidjanov, Kerkadze, Büchler, Zöller, Schmidt: "Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer." in: Pancreas, Vol. 38, Issue 7, pp. 804-10, (2009) (PubMed).

Huang, Zhang, Kim, Ge, Annis, Mosher, Greenspan: "Fibronectin binds and enhances the activity of bone morphogenetic protein 1." in: The Journal of biological chemistry, Vol. 284, Issue 38, pp. 25879-88, (2009) (PubMed).

Details zu Fibronectin 1

Target: Fibronectin 1 (FN1)

Andere Bezeichnung: FN1

Hintergrund: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.

Molekulargewicht: 262.6 kDa

Gen-ID: 2335

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie