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Fibulin 5 Antikörper (AA 242-448)

Der Maus Monoklonal Anti-Fibulin 5-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, Fibulin 5 in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.
Produktnummer ABIN969131

Kurzübersicht für Fibulin 5 Antikörper (AA 242-448) (ABIN969131)

Target

Alle Fibulin 5 (FBLN5) Antikörper anzeigen
Fibulin 5 (FBLN5)

Reaktivität

  • 69
  • 40
  • 29
  • 1
Human

Wirt

  • 70
  • 9
  • 1
Maus

Klonalität

  • 69
  • 13
Monoklonal

Konjugat

  • 40
  • 9
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Fibulin 5 Antikörper ist unkonjugiert

Applikation

  • 64
  • 28
  • 25
  • 16
  • 13
  • 4
  • 4
  • 1
Immunohistochemistry (IHC), ELISA

Klon

1G6A4
  • Bindungsspezifität

    • 12
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 242-448

    Verwendungszweck

    FBLN5 Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

    Stone, Braun, Russell, Kuehn, Lotery, Moore, Eastman, Casavant, Sheffield: "Missense variations in the fibulin 5 gene and age-related macular degeneration." in: The New England journal of medicine, Vol. 351, Issue 4, pp. 346-53, (2004) (PubMed).

    Markova, Zou, Ringpfeil, Sasaki, Kostka, Timpl, Uitto, Chu: "Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene." in: American journal of human genetics, Vol. 72, Issue 4, pp. 998-1004, (2003) (PubMed).

  • Target

    Fibulin 5 (FBLN5)

    Andere Bezeichnung

    FBLN5

    Hintergrund

    FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.

    UniProt

    Q9UBX5

    Pathways

    SARS-CoV-2 Protein Interaktom
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