ERN1 Antikörper (AA 282-433)

Produktnummer ABIN969116

Der Maus Monoklonal Anti-ERN1-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, ERN1 in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für ERN1 Antikörper (AA 282-433) (ABIN969116)

Target: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ERN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 9F2

Produktdetails anti-ERN1 Antikörper

Bindungsspezifität: AA 282-433

Verwendungszweck: ERN1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human ERN1(aa282-433) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-ERN1 Antikörper (ABIN969116)

Lin, Li, Yasumura, Cohen, Zhang, Panning, Shokat, Lavail, Walter: "IRE1 signaling affects cell fate during the unfolded protein response." in: Science (New York, N.Y.), Vol. 318, Issue 5852, pp. 944-9, (2007) (PubMed).

Huang, Tan, Yoshida, Mori, Ma, Yen: "Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress." in: Molecular and cellular biology, Vol. 25, Issue 17, pp. 7522-33, (2005) (PubMed).

Shang, Lehrman: "Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts." in: Biochemical and biophysical research communications, Vol. 317, Issue 2, pp. 390-6, (2004) (PubMed).

Details zu ERN1

Target: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Andere Bezeichnung: ERN1

Hintergrund: The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Molekulargewicht: 109 kDa

UniProt: O75460

Pathways: ER-Nucleus Signaling, Unfolded Protein Response