EPH Receptor B4 Antikörper
(2 Referenzen)Kurzübersicht für EPH Receptor B4 Antikörper (ABIN969107)
Target
Alle EPH Receptor B4 (EPHB4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- EphB4 Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of EphB4 expressed in E. Coli.
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Isotyp
- IgG2a
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anti-EPH Receptor B4 (EPHB4) (AA 472-486), (Extracellular) antibody
EPHB4 Reaktivität: Maus WB, IHC, IF, FACS, LCI Wirt: Kaninchen Polyclonal unconjugated
anti-EPH Receptor B4 (EPHB4) (AA 300-540) antibodyEPHB4 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-EPH Receptor B4 (EPHB4) antibodyEPHB4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB14731 unconjugated
anti-EPH Receptor B4 (EPHB4) antibodyEPHB4 Reaktivität: Human ELISA, ICC Wirt: Maus Monoclonal 5B5 unconjugated
anti-EPH Receptor B4 (EPHB4) (AA 562-612) antibodyEPHB4 Reaktivität: Human ELISA Wirt: Maus Monoclonal 7H4A6 unconjugated
anti-EPH Receptor B4 (EPHB4) (AA 198-323) antibodyEPHB4 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4G11 unconjugated
anti-EPH Receptor B4 (EPHB4) (Internal Region) antibodyEPHB4 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-EPH Receptor B4 (EPHB4) (Internal Region) antibodyEPHB4 Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-EPH Receptor B4 (EPHB4) (AA 889-923), (C-Term) antibodyEPHB4 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB50408 unconjugated
anti-EPH Receptor B4 (EPHB4) antibodyEPHB4 Reaktivität: Human WB Wirt: Maus Monoclonal 67CT23-5-8 unconjugated
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity." in: Structure (London, England : 1993), Vol. 14, Issue 2, pp. 321-30, (2006) (PubMed).
: "Expression of Ephb2 and Ephb4 in breast carcinoma." in: Pathology oncology research : POR, Vol. 10, Issue 1, pp. 26-33, (2004) (PubMed).
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: "Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity." in: Structure (London, England : 1993), Vol. 14, Issue 2, pp. 321-30, (2006) (PubMed).
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- EPH Receptor B4 (EPHB4)
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Andere Bezeichnung
- EphB4
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Hintergrund
- EPH receptor B4 (EphB4), with 987-amino acid protein (about 108 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptor tyrosine kinases and their ligands, the ephrins, regulate numerous biological processes in developing and adult tissues and have been implicated in cancer progression and in pathological forms of angiogenesis. EphB4 acts as a negative regulator of blood vessel branching and vascular network formation, switching the vascularization program from sprouting angiogenesis to circumferential vessel growth. EphB4 and its ligand ephrinB2 express in several kinds of tumor cells and correlate with tumorigenesis. EphB4 is thus a potential candidate as a predictor of disease outcome in several kinds of tumor and as target for novel therapy.
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UniProt
- P54760
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Pathways
- RTK Signalweg
Target
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