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CDC27 Antikörper

Der Maus Monoklonal Anti-CDC27-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, CDC27 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.
Produktnummer ABIN969035

Kurzübersicht für CDC27 Antikörper (ABIN969035)

Target

Alle CDC27 Antikörper anzeigen
CDC27 (Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27))

Reaktivität

  • 71
  • 47
  • 29
  • 8
  • 8
  • 6
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 82
  • 5
Maus

Klonalität

  • 74
  • 13
Monoklonal

Konjugat

  • 35
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser CDC27 Antikörper ist unkonjugiert

Applikation

  • 30
  • 27
  • 27
  • 23
  • 13
  • 11
  • 9
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)

Klon

5C12
  • Verwendungszweck

    CDC27 Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human CDC27 expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Goto, Eddy: "Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 42128-38, (2004) (PubMed).

    Koloteva-Levine, Pinchasi, Pereman, Zur, Brandeis, Elroy-Stein: "The Apc5 subunit of the anaphase-promoting complex/cyclosome interacts with poly(A) binding protein and represses internal ribosome entry site-mediated translation." in: Molecular and cellular biology, Vol. 24, Issue 9, pp. 3577-87, (2004) (PubMed).

  • Target

    CDC27 (Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27))

    Andere Bezeichnung

    CDC27

    Hintergrund

    Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.

    Molekulargewicht

    91 kDa

    Gen-ID

    996

    UniProt

    P30260
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