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CDC27 Antikörper (Cell Division Cycle 27 Homolog (S. Cerevisiae)) Middle Region Primary Antibody

CDC27 Reaktivität: Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781488
$389.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle CDC27 Antikörper anzeigen
    CDC27
    Bindungsspezifität
    • 17
    • 15
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 67
    • 44
    • 28
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen
    Wirt
    • 75
    • 7
    Kaninchen
    Klonalität
    • 67
    • 15
    Polyklonal
    Konjugat
    • 34
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CDC27 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 27
    • 26
    • 22
    • 14
    • 13
    • 11
    • 6
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Sequenz
    KLKMKFPPKI PNRKTKSKTN KGGITQPNIN DSLEITKLDS SIISEGKIST
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CDC27. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CDC27
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 824 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CDC27
    Andere Bezeichnung
    CDC27 (CDC27 Produkte)
    Synonyme
    ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2, wu:fb54g06, wu:fc88c12, AI452358, BC023187, CDC27, NV10210, cell division cycle 27, cell division cycle 27 S homeolog, cell division cycle protein 27 homolog, anaphase-promoting complex subunit Apc3, CDC27, cdc27, Cdc27, cdc27.S, LOC100123129, nuc2
    Hintergrund
    The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2, ANAPC3
    Protein Interaction Partner: ANAPC2, UBE2S, PTTG1, FBXO43, MAD2L1, COMT, CDC20, CCNB1, BUB1B, UBC, BIRC6, ANAPC4, CDH1, FZR1, MIB1, HECW2, ANAPC11, PHF8, CUEDC2, Sirt2, Dlg4, GKN1, ANAPC7, ANAPC5, DCPS, ADNP, MDC1, PTEN, TRIM33, REV1, ANAPC15, VCP, MAD2L2, NOTCH1, PAXIP1, UBE4B, TTK,
    Protein Size: 824
    Molekulargewicht
    92 kDa
    Gen-ID
    996
    NCBI Accession
    NM_001256, NP_001247
    UniProt
    P30260
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