Cyclin B1 Antikörper

Produktnummer ABIN969005

Der Maus Monoklonal Anti-Cyclin B1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, Cyclin B1 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Cyclin B1 Antikörper (ABIN969005)

Target: Cyclin B1 (CCNB1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cyclin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 1B10

Produktdetails anti-Cyclin B1 Antikörper

Verwendungszweck: CCNB1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CCNB1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Cyclin B1 Antikörper (ABIN969005)

Zhang, Li, Guo, Cao, Zhao, Jiang, Ma, Yi, Li, Jiang, Wu, Wang, Si: "DH166, a beta-carboline derivative, inhibits the kinase activity of PLK1." in: Cancer biology & therapy, Vol. 8, Issue 24, pp. 2374-83, (2010) (PubMed).

Okayama, Kumamoto, Saitou, Hayase, Kofunato, Sato, Miyamoto, Nakamura, Ohki, Sekikawa, Takenoshita: "CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer." in: Oncology reports, Vol. 22, Issue 4, pp. 745-55, (2009) (PubMed).

Details zu Cyclin B1

Target: Cyclin B1 (CCNB1)

Andere Bezeichnung: CCNB1

Hintergrund: The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. (provided by RefSeq) It has higher expression in tumor tissues .

Molekulargewicht: 60 kDa

Gen-ID: 891

UniProt: P14635

Pathways: Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase