BMI1 Antikörper
(2 Referenzen)Kurzübersicht für BMI1 Antikörper (ABIN968985)
Target
Alle BMI1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- BMI1 Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human BMI1 expressed in E. Coli.
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Isotyp
- IgG1
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anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) antibody
BMI1 Reaktivität: Human, Maus WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB22858 unconjugated
anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (AA 120-326) antibodyBMI1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (AA 142-326) antibodyBMI1 Reaktivität: Human, Maus WB, IHC, IF, StM Wirt: Maus Monoclonal BMI1-2823 unconjugated
anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (AA 1-326) antibodyBMI1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4E10-1C5 unconjugated
anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (AA 142-326) antibodyBMI1 Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal BMI1-2689 unconjugated
anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (AA 257-286), (C-Term) antibodyBMI1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB02926 unconjugated
anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (AA 142-326) antibodyBMI1 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal BMI1-2690 unconjugated
anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (AA 257-286) antibodyBMI1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (AA 1-247) antibodyBMI1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (AA 61-160) antibodyBMI1 Reaktivität: Human WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer." in: Cancer research, Vol. 69, Issue 16, pp. 6423-9, (2009) (PubMed).
: "MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer." in: Cancer research, Vol. 69, Issue 23, pp. 9090-5, (2009) (PubMed).
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: "Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer." in: Cancer research, Vol. 69, Issue 16, pp. 6423-9, (2009) (PubMed).
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Andere Bezeichnung
- BMI1
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Hintergrund
- Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
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Molekulargewicht
- 37 kDa
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Gen-ID
- 648
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UniProt
- P35226
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Pathways
- Zellzyklus, Autophagie
Target
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