LIN28A Antikörper (AA 93-209)

Produktnummer ABIN968936

Der Maus Monoklonal Anti-LIN28A-Antikörper wurde für ELISA und ICC validiert. Er ist geeignet, LIN28A in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für LIN28A Antikörper (AA 93-209) (ABIN968936)

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LIN28A Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC)

Klon: 6D1F9

Produktdetails anti-LIN28A Antikörper

Bindungsspezifität: AA 93-209

Verwendungszweck: LIN28 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-LIN28A Antikörper (ABIN968936)

Gerecht-Nir, Dazard, Golan-Mashiach, Osenberg, Botvinnik, Amariglio, Domany, Rechavi, Givol, Itskovitz-Eldor: "Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem cells." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 232, Issue 2, pp. 487-97, (2005) (PubMed).

Wu, Belasco: "Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9198-208, (2005) (PubMed).

Details zu LIN28A

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Andere Bezeichnung: LIN28

Hintergrund: LIN28: lin-28 homolog (C. elegans), also known as CSDD1, ZCCHC1. Entrez Protein NP_078950. LIN28 was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation.

Molekulargewicht: 23 kDa

Gen-ID: 79727

UniProt: Q9H9Z2

Pathways: Stem Cell Maintenance