LIN28A Antikörper (AA 142-209)
Kurzübersicht für LIN28A Antikörper (AA 142-209) (ABIN6143238)
Target
Alle LIN28A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 142-209
-
Sequenz
- CGGLDHHAKE CKLPPQPKKC HFCQSISHMV ASCPLKAQQG PSAQGKPTYF REEEEEIHSP TLLPEAQN
-
Kreuzreaktivität
- Human, Maus
-
Produktmerkmale
- Polyclonal Antibodies
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 142-209 of human LIN28 (NP_078950.1).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
-
Andere Bezeichnung
- LIN28A
-
Hintergrund
- This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.,LIN28A,CSDD1,LIN-28,LIN28,ZCCHC1,lin-28A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,Embryonic Stem Cells,LIN28A
-
Molekulargewicht
- 22 kDa
-
Gen-ID
- 79727
-
UniProt
- Q9H9Z2
-
Pathways
- Stem Cell Maintenance
Target
-