RAC1 Antikörper
-
- Target Alle RAC1 Antikörper anzeigen
- RAC1
-
Reaktivität
- Human, Maus, Ratte, Hund, Huhn
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser RAC1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Kreuzreaktivität
- Huhn, Hund, Maus, Ratte (Rattus)
- Produktmerkmale
-
Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Positive Control: Rat Cerebrum - Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Klon
- 102-Rac1
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product RAC1 Primärantikörper
-
-
- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Aqueous buffered solution containing BSA, glycerol.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store undiluted at -20°C.
-
- Target
- RAC1
- Abstract
- RAC1 Produkte
- Synonyme
- Rac-1 antikoerper, TC-25 antikoerper, p21-Rac1 antikoerper, AL023026 antikoerper, D5Ertd559e antikoerper, RAC2 antikoerper, CRAC1A antikoerper, rac1 antikoerper, wu:fd16e02 antikoerper, zgc:55823 antikoerper, zgc:55917 antikoerper, zgc:86934 antikoerper, 2248 antikoerper, CG2248 antikoerper, D-Rac antikoerper, D-Rac 1 antikoerper, D-Rac1 antikoerper, DRac antikoerper, DRac1 antikoerper, DRacA antikoerper, Dm Rac1 antikoerper, DmRAC antikoerper, DmRAC1 antikoerper, Dmel\CG2248 antikoerper, Dmrac1 antikoerper, Drac antikoerper, Drac1 antikoerper, Drac1a antikoerper, DracA antikoerper, GTPase Rac1 antikoerper, P40792 antikoerper, RAC1 antikoerper, Rac antikoerper, Rac GTPase antikoerper, Rac3 antikoerper, RacA antikoerper, dRac antikoerper, dRac1 antikoerper, drac1 antikoerper, rac antikoerper, Xrac antikoerper, mig5 antikoerper, p21-rac1 antikoerper, tc-25 antikoerper, Rac family small GTPase 1 antikoerper, RAS-related C3 botulinum substrate 1 antikoerper, ras-related C3 botulinum toxin substrate 1 antikoerper, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antikoerper, Rac family small GTPase 1a antikoerper, CG2248 gene product from transcript CG2248-RB antikoerper, Rac family small GTPase 1 L homeolog antikoerper, ras homolog family member G antikoerper, RAC1 antikoerper, Rac1 antikoerper, rac1a antikoerper, rac1.L antikoerper, RHOG antikoerper
- Hintergrund
-
Rac1 is a member of the expanding family of Ras-related GTPase proteins. These small proteins have the ability to switch between two different conformational states: the active (GTP-bound) and the inactive (GDP-bound). The GTPase activity is increased by specific activator proteins named GAPs. Rac1, contains the consensus sequence Cys-X-X-X-COOH, which localizes it to the plasma membrane. Growth factor stimulation of cells results in a dramatic reorganization of the actin filament network and membrane ruffling, processes for which Rac1 is essential. Constitutive expression of Rac1 leads to cell transformation. This process is mediated by the Rac1-dependent activation of the p65PAK serine/threonine kinase. IQGAP1 has been identified as a GTPase activating protein specific for Rac1.
Testing in native ELISA with recombinant proteins to CDC42 and Rho have shown that the antibody to Rac1 (cat No ABIN968088/1) recognizes CDC42 and Rho. Due to sequence homology among various small GTPase familyl members, potential reactivity could be observed with other family members. - Molekulargewicht
- 21 kDa
- Pathways
- WNT Signalweg, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling
-