S100B Antikörper

Produktnummer ABIN966987

Produktdetails anti-S100B Antikörper

Target: S100B (S100 Calcium Binding Protein B (S100B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of S100B expressed in E. Coli.

Klon: 9A11B9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-S100B Antikörper (ABIN966987)

Sorci, Riuzzi, Arcuri, Giambanco, Donato: "Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE binding." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4880-94, (2004) (PubMed).

Details zu S100B

Target: S100B (S100 Calcium Binding Protein B (S100B))

Andere Bezeichnung: S100B (S100B Produkte)

Synonyme: NEF antikoerper, S100 antikoerper, S100-B antikoerper, S100beta antikoerper, S100P antikoerper, AI850290 antikoerper, Bpb antikoerper, si:dkey-110p14.2 antikoerper, wu:fq18b10 antikoerper, zgc:92776 antikoerper, S100 calcium binding protein B antikoerper, S100 protein, beta polypeptide, neural antikoerper, S100 calcium binding protein, beta (neural) antikoerper, S100B antikoerper, S100b antikoerper, s100b antikoerper

Hintergrund: S100B (S100 calcium binding protein B) is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S100B are present in a variety of other tissues, and calbindin is present in intestine and kidney. Parvalbumin B is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Synonyms: NEF, S100, S100beta

Gen-ID: 6285

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine