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Rekombinanter S100B Antikörper

S100B Reaktivität: Human, Ratte, Maus, Rind (Kuh) IHC, StM Wirt: Maus Monoclonal rS100B-1012 unconjugated Recombinant Antibody
Produktnummer ABIN6940559
  • Target Alle S100B Antikörper anzeigen
    S100B (S100 Calcium Binding Protein B (S100B))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 157
    • 93
    • 62
    • 43
    • 18
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Rind (Kuh)
    Wirt
    • 127
    • 66
    • 7
    • 2
    • 2
    • 1
    Maus
    Klonalität
    • 114
    • 91
    Monoklonal
    Konjugat
    • 84
    • 31
    • 21
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser S100B Antikörper ist unkonjugiert
    Applikation
    • 141
    • 79
    • 64
    • 60
    • 48
    • 25
    • 25
    • 19
    • 18
    • 15
    • 13
    • 9
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human S100B protein
    Klon
    RS100B-1012
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product S100B Primärantikörper
  • Applikationshinweise

    Positive Control: Brain, Melanoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    S100B (S100 Calcium Binding Protein B (S100B))
    Andere Bezeichnung
    S100B (S100B Produkte)
    Synonyme
    NEF antikoerper, S100 antikoerper, S100-B antikoerper, S100beta antikoerper, S100P antikoerper, AI850290 antikoerper, Bpb antikoerper, si:dkey-110p14.2 antikoerper, wu:fq18b10 antikoerper, zgc:92776 antikoerper, S100 calcium binding protein B antikoerper, S100 protein, beta polypeptide, neural antikoerper, S100 calcium binding protein, beta (neural) antikoerper, S100B antikoerper, S100b antikoerper, s100b antikoerper
    Molekulargewicht
    10-12kDa
    Gen-ID
    6285
    UniProt
    P04271
    Pathways
    Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine
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