S100B Antikörper

Produktnummer ABIN969391

Produktdetails anti-S100B Antikörper

Target: S100B (S100 Calcium Binding Protein B (S100B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of S100B expressed in E. coli.

Klon: 9A11B9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-S100B Antikörper (ABIN969391)

Zimmer, Chaplin, Baldwin, Rast: "S100-mediated signal transduction in the nervous system and neurological diseases." in: Cellular and molecular biology (Noisy-le-Grand, France), Vol. 51, Issue 2, pp. 201-14, (2005) (PubMed).

Sorci, Riuzzi, Arcuri, Giambanco, Donato: "Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE binding." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4880-94, (2004) (PubMed).

Shapiro, Marks, Whitaker-Azmitia: "Increased clusterin expression in old but not young adult S100B transgenic mice: evidence of neuropathological aging in a model of Down Syndrome." in: Brain research, Vol. 1010, Issue 1-2, pp. 17-21, (2004) (PubMed).

Details zu S100B

Target: S100B (S100 Calcium Binding Protein B (S100B))

Andere Bezeichnung: S100B (S100B Produkte)

Synonyme: NEF antikoerper, S100 antikoerper, S100-B antikoerper, S100beta antikoerper, S100P antikoerper, AI850290 antikoerper, Bpb antikoerper, si:dkey-110p14.2 antikoerper, wu:fq18b10 antikoerper, zgc:92776 antikoerper, S100 calcium binding protein B antikoerper, S100 protein, beta polypeptide, neural antikoerper, S100 calcium binding protein, beta (neural) antikoerper, S100B antikoerper, S100b antikoerper, s100b antikoerper

Hintergrund:

Description: S100B (S100 calcium binding protein B) is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S100B are present in a variety of other tissues, and calbindin is present in intestine and kidney. Parvalbumin B is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Aliases: NEF, S100, S100beta

Gen-ID: 6285

HGNC: 6285

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine