Dieses Anti-IL-8-Antikörper ist ein Monoklonal-Antikörper zur Detektion von IL-8 in WB und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
IL8
Reaktivität: Human
WB, IHC, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Dilution: Western Blot: 1:500-1,000 ELISA: 1,000-2,000. Determining optimal working dilutions by titration test.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Lagerung
-20 °C
Baggiolini, Clark-Lewis: "Interleukin-8, a chemotactic and inflammatory cytokine." in: FEBS letters, Vol. 307, Issue 1, pp. 97-101, (1992) (PubMed).
Mukaida, Shiroo, Matsushima: "Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 143, Issue 4, pp. 1366-71, (1989) (PubMed).
Target
IL-8 (IL8)
(Interleukin 8 (IL8))
Andere Bezeichnung
IL-8
Hintergrund
Interleukin-8 (IL-8)is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.