HSP27 Antikörper

Produktnummer ABIN966313

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HSP27 in IHC. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 3+ Publikationen zitiert.

Kurzübersicht für HSP27 Antikörper (ABIN966313)

Target: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSP27 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-HSP27 Antikörper

Spezifität: HSP27 (Ab-78) antibody detects endogenous levels of total HSP27 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human HSP27 around the phosphorylation site of serine 78 (A-L-SP-R-Q).

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000
IHC: 1:50~1:100.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-HSP27 Antikörper (ABIN966313)

Somara, Bitar: "Tropomyosin interacts with phosphorylated HSP27 in agonist-induced contraction of smooth muscle." in: American journal of physiology. Cell physiology, Vol. 286, Issue 6, pp. C1290-301, (2004) (PubMed).

Jordan, Brownstone, Noga: "Control of functional systems in the brainstem and spinal cord." in: Current opinion in neurobiology, Vol. 2, Issue 6, pp. 794-801, (1993) (PubMed).

Landry, Lambert, Zhou, Lavoie, Hickey, Weber, Anderson: "Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II." in: The Journal of biological chemistry, Vol. 267, Issue 2, pp. 794-803, (1992) (PubMed).

Details zu HSP27

Target: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Andere Bezeichnung: HSP27

Pathways: MAPK Signalweg, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling