Fibulin 5 Antikörper

Produktnummer ABIN966144

Dieses Anti-Fibulin 5-Antikörper ist ein Monoklonal-Antikörper zur Detektion von Fibulin 5 in WB und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für Fibulin 5 Antikörper (ABIN966144)

Target: Fibulin 5 (FBLN5)

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser Fibulin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Fibulin 5 Antikörper

Spezifität: Ni-NTA purified truncated recombinant Fibulin 5 expressed in E. Coli strain BL21 (DE3)

Aufreinigung: Crude ascites.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 500- 1: 2000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Referenzen für anti-Fibulin 5 Antikörper (ABIN966144)

Wen, Hochholdinger, Sauer, Bruce, Schnable: "The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis." in: Plant physiology, Vol. 138, Issue 3, pp. 1637-43, (2005) (PubMed).

Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." in: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, (2005) (PubMed).

Lee, Roy, Mogford, Schiemann, Mustoe: "Fibulin-5 promotes wound healing in vivo." in: Journal of the American College of Surgeons, Vol. 199, Issue 3, pp. 403-10, (2004) (PubMed).

Details zu Fibulin 5

Target: Fibulin 5 (FBLN5)

Andere Bezeichnung: Fibulin 5

Hintergrund: Fibulin 5(FBLN5), with 448-amino acid protein (about 50kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

Pathways: SARS-CoV-2 Protein Interaktom