CREB1 Antikörper (cAMP Responsive Element Binding Protein 1)

Details for Product anti-CREB1 Antibody No. ABIN965927
Antigen
Reaktivität
Human, Maus, Ratte (Rattus)
574
358
325
42
35
32
31
26
22
16
15
13
13
6
6
5
2
1
1
1
1
Wirt
Kaninchen
509
72
7
1
Klonalität
Polyklonal
Konjugat
Dieser CREB1 Antikörper ist unkonjugiert
26
15
15
13
13
13
13
13
13
8
7
6
3
3
3
3
3
1
Applikation
Immunohistochemistry (IHC)
435
237
224
90
89
50
45
44
23
14
11
10
4
4
2
2
1
1
Optionen
Immunogen This antiserum was produced against synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 133 (R-P-SP-Y-R).
Spezifität CREB (Ab-133) antibody detects endogenous levels of total CREB protein.
Reinigung The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Antigen
Andere Bezeichnung CREB (CREB1 Antibody Abstract)
Pathways TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
Applikations-hinweise WB: 1:500~1:1000
IHC: 1:50~1:100.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Produkt verwendet in: Westerheide, Mayo, Anest, Hanson, Baldwin: "The putative oncoprotein Bcl-3 induces cyclin D1 to stimulate G(1) transition." in: Molecular and cellular biology, Vol. 21, Issue 24, pp. 8428-36, 2001 (PubMed).

Xing, Kornhauser, Xia, Thiele, Greenberg: "Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation." in: Molecular and cellular biology, Vol. 18, Issue 4, pp. 1946-55, 1998 (PubMed).

Rosenfeld, Correia, Xing, Rener, Cheung: "Structural studies of kinesin-nucleotide intermediates." in: The Journal of biological chemistry, Vol. 271, Issue 47, pp. 30212-21, 1997 (PubMed).

Tan, Rouse, Zhang, Cariati, Cohen, Comb: "FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2." in: The EMBO journal, Vol. 15, Issue 17, pp. 4629-42, 1997 (PubMed).

Hao, Lowy, Kapoor, Deffie, Liu, Lozano: "Mutation of phosphoserine 389 affects p53 function in vivo." in: The Journal of biological chemistry, Vol. 271, Issue 46, pp. 29380-5, 1997 (PubMed).