CHEK2 Antikörper
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- Target Alle CHEK2 Antikörper anzeigen
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHEK2 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Spezifität
- Chk2 (Ab-68) antibody detects endogenous levels of total Chk2 protein.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human Chk2 around the phosphorylation site of threonine 68.
- Top Product
- Discover our top product CHEK2 Primärantikörper
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- Applikationshinweise
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WB: 1:500~1:1000
IHC: 1:50~1:100. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100ug/100ul.
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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ATM-dependent phosphorylation of ATF2 is required for the DNA damage response." in: Molecular cell, Vol. 18, Issue 5, pp. 577-87, (2005) (PubMed).
: "Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions." in: Nature, Vol. 434, Issue 7035, pp. 907-13, (2005) (PubMed).
: "Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis." in: Oncogene, Vol. 24, Issue 12, pp. 1973-81, (2005) (PubMed).
: "Regulation of CHK2 by DNA-dependent protein kinase." in: The Journal of biological chemistry, Vol. 280, Issue 12, pp. 12041-50, (2005) (PubMed).
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ATM-dependent phosphorylation of ATF2 is required for the DNA damage response." in: Molecular cell, Vol. 18, Issue 5, pp. 577-87, (2005) (PubMed).
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- Target
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
- Andere Bezeichnung
- CHK2 (CHEK2 Produkte)
- Pathways
- p53 Signalweg, Apoptose, Zellzyklus
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