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CDK9 Antikörper

CDK9 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 1B5D10 unconjugated
Produktnummer ABIN965846
  • Target Alle CDK9 Antikörper anzeigen
    CDK9 (Cyclin-Dependent Kinase 9 (CDK9))
    Reaktivität
    • 94
    • 46
    • 20
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 91
    • 3
    • 2
    Maus
    Klonalität
    • 82
    • 14
    Monoklonal
    Konjugat
    • 43
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CDK9 Antikörper ist unkonjugiert
    Applikation
    • 78
    • 33
    • 26
    • 26
    • 15
    • 13
    • 12
    • 11
    • 10
    • 8
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human CDK9 expressed in E. Coli.
    Klon
    1B5D10
    Isotyp
    IgG1
    Top Product
    Discover our top product CDK9 Primärantikörper
  • Applikationshinweise
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Montanuy, Torremocha, Hernández-Munain, Suñé: "Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9." in: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7368-78, (2008) (PubMed).

    Sabò, Lusic, Cereseto, Giacca: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).

  • Target
    CDK9 (Cyclin-Dependent Kinase 9 (CDK9))
    Andere Bezeichnung
    CDK9 (CDK9 Produkte)
    Synonyme
    C-2k antikoerper, CDC2L4 antikoerper, CTK1 antikoerper, PITALRE antikoerper, TAK antikoerper, wu:fb22e09 antikoerper, wu:fc06c02 antikoerper, c-2k antikoerper, cdc2l4 antikoerper, cdk9 antikoerper, ctk1 antikoerper, pitalre antikoerper, tak antikoerper, CDK9 antikoerper, CG5179 antikoerper, Dmel\\CG5179 antikoerper, P-TEF antikoerper, P-TEFb antikoerper, PTefb antikoerper, cyclin dependent kinase 9 antikoerper, cyclin-dependent kinase 9 (CDC2-related kinase) antikoerper, cyclin-dependent kinase 9 L homeolog antikoerper, cyclin-dependent kinase 9 antikoerper, Cyclin-dependent kinase 9 antikoerper, cyclin-dependent kinase 9 S homeolog antikoerper, CDK9 antikoerper, cdk9 antikoerper, cdk9.L antikoerper, Cdk9 antikoerper, cdk9.S antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
    Tissue specificity: Ubiquitous.
    Synonyms: TAK, C-2k, CTK1, CDC2L4, PITALRE
    Molekulargewicht
    43kDa
    Gen-ID
    1025
    Pathways
    Zellzyklus
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