CA8 Antikörper (N-Term)

Produktnummer ABIN965733

Dieses Anti-CA8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CA8 in IHC. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für CA8 Antikörper (N-Term) (ABIN965733)

Target: CA8 (Carbonic Anhydrase VIII (CA8))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CA8 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-CA8 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human CA8(Carbonic anhydrase VIII)

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-CA8 Antikörper (ABIN965733)

Hirota, Ando, Hamada, Mikoshiba: "Carbonic anhydrase-related protein is a novel binding protein for inositol 1,4,5-trisphosphate receptor type 1." in: The Biochemical journal, Vol. 372, Issue Pt 2, pp. 435-41, (2003) (PubMed).

Taniuchi, Nishimori, Takeuchi, Fujikawa-Adachi, Ohtsuki, Onishi: "Developmental expression of carbonic anhydrase-related proteins VIII, X, and XI in the human brain." in: Neuroscience, Vol. 112, Issue 1, pp. 93-9, (2002) (PubMed).

Bergenhem, Sait, Eddy, Shows, Tashian: "Assignment of the gene for human carbonic anhydrase VIII(CA8) to chromosome 8q11-->q12." in: Cytogenetics and cell genetics, Vol. 71, Issue 3, pp. 299-300, (1995) (PubMed).

Kelly, Nógrádi, Walker, Caddy, Peters, Carter: "Lurching, reeling, waddling and staggering in mice--is carbonic anhydrase (CA) VIII a candidate gene?" in: Biochemical Society transactions, Vol. 22, Issue 3, pp. 359S, (1995) (PubMed).

Skaggs, Bergenhem, Venta, Tashian: "The deduced amino acid sequence of human carbonic anhydrase-related protein (CARP) is 98% identical to the mouse homologue." in: Gene, Vol. 126, Issue 2, pp. 291-2, (1993) (PubMed).

Details zu CA8

Target: CA8 (Carbonic Anhydrase VIII (CA8))

Andere Bezeichnung: CA8

Hintergrund: CA8(Carbonic anhydrase VIII) was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, Carbonic anhydrase VIII lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The Carbonic anhydrase VIII continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Carbonic anhydrase VIII belongs to the eukaryotic-type carbonic anhydrase family.