ABL1 Antikörper

Produktnummer ABIN965709

Dieses Anti-ABL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ABL1 in IHC. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für ABL1 Antikörper (ABIN965709)

Target: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABL1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-ABL1 Antikörper

Spezifität: C-Abl (Ab-412) antibody detects endogenous levels of total c-Abl protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human c-Abl around the phosphorylation site of tyrosine 412 (D-T-YP-T-A).

Anwendungsinformationen

Applikationshinweise: IHC: 1:50-1:100.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-ABL1 Antikörper (ABIN965709)

Kawai, Nie, Yuan: "Inactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6079-88, (2002) (PubMed).

Yoshida, Komatsu, Wang, Kufe: "c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3292-300, (2002) (PubMed).

Sionov, Coen, Goldberg, Berger, Bercovich, Ben-Neriah, Ciechanover, Haupt: "c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination." in: Molecular and cellular biology, Vol. 21, Issue 17, pp. 5869-78, (2001) (PubMed).

Kharbanda, Pandey, Yamauchi, Kumar, Kaneki, Kumar, Bharti, Yuan, Ghanem, Rana, Weichselbaum, Johnson, Kufe: "Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage." in: Molecular and cellular biology, Vol. 20, Issue 14, pp. 4979-89, (2000) (PubMed).

Details zu ABL1

Target: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Andere Bezeichnung: C-Abl

Pathways: Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism