Aurora A Antikörper
(2 Referenzen)-
- Target Alle Aurora A (AURKA) Antikörper anzeigen
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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Reaktivität
- Human, Ratte, Affe
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Aurora A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human AURKA expressed in E. Coli.
- Klon
- 1F8
- Isotyp
- IgG1
- Top Product
- Discover our top product AURKA Primärantikörper
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anti-Aurora Kinase A (AURKA) (AA 1-110) antibody
AURKA Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 5F8 unconjugated
anti-Aurora Kinase A (AURKA) (AA 268-404) antibodyAURKA Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 2D8A4 unconjugated
anti-Aurora Kinase A (AURKA) (C-Term) antibodyAURKA Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 364-392), (C-Term) antibodyAURKA Reaktivität: Human WB, IF, FACS Wirt: Kaninchen Polyclonal RB6834 unconjugated
anti-Aurora Kinase A (AURKA) antibodyAURKA Reaktivität: Human WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 1F8 unconjugated
anti-Aurora Kinase A (AURKA) antibodyAURKA Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 4G10 unconjugated
anti-Aurora Kinase A (AURKA) (AA 268-404) antibodyAURKA Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 4H5A8 unconjugated
anti-Aurora Kinase A (AURKA) (pThr288) antibodyAURKA Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 364-392) antibodyAURKA Reaktivität: Human WB, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 1-131) antibodyAURKA Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
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: "Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity." in: Oncogene, Vol. 27, Issue 51, pp. 6539-49, (2008) (PubMed).
: "AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3525-33, (2008) (PubMed).
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: "Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity." in: Oncogene, Vol. 27, Issue 51, pp. 6539-49, (2008) (PubMed).
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- Target
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
- Andere Bezeichnung
- AURKA (AURKA Produkte)
- Hintergrund
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Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
Synonyms: AIK, ARK1, AURA, BTAK, STK6, - Molekulargewicht
- 48kDa
- Gen-ID
- 6790
- Pathways
- Zellzyklus, Asymmetric Protein Localization
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